| Humphries Brook | |
| Pushpin Map: | New York |
| Pushpin Map Caption: | Location of the mouth of Humphries Brook |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | New York |
| Subdivision Type4: | County |
| Subdivision Name4: | Delaware |
| Source1 Coordinates: | 41.9101°N -75.2354°W |
| Mouth: | Delaware River |
| Mouth Coordinates: | 41.8684°N -75.2143°W[1] |
| Mouth Elevation: | 860feet |
Humphries Brook is a river in Delaware County, New York. It flows into Somerset Lake from the west, then exits the lake and flows south before converging with the Delaware River in Lordville.