Human parechovirus 1 (HPeV1) cis regulatory element (CRE) explained

Human parechovirus 1 (HPeV1) cis regulatory element (CRE)
Symbol:	Parecho_CRE
Rfam:	RF00499
Rna Type:	Cis-reg
Tax Domain:	Viruses

The Human Parechovirus 1 cis regulatory element is an RNA element which is located in the 5'-terminal 112 nucleotides of the genome of human parechovirus 1 (HPeV1). The element consists of two stem-loop structures (SL-A and SL-B) together with a pseudoknot. Disruption of any of these elements impairs both viral replication and growth.^[1]

See also

• Human rhinovirus internal cis-acting regulatory element (CRE)
• Rotavirus cis-acting replication element (CRE)
• Parechovirus

Notes and References

1. Nateri AS, Hughes PJ, Stanway G . Terminal RNA replication elements in human parechovirus 1 . Journal of Virology . 76 . 24 . 13116–13122 . December 2002 . 12438643 . 136667 . 10.1128/JVI.76.24.13116-13122.2002 .