| Huaquillas | |
| Settlement Type: | City |
| Total Type: | City |
| Motto: | Spanish; Castilian: Centinela sin relevo (Sentinel without relief) |
| Nickname: | Spanish; Castilian: Huaquillas, ciudad binacional (Huaquillas, binational city) |
| Pushpin Map: | Ecuador |
| Coordinates: | -3.475°N -80.2183°W |
| Subdivision Type: | Country |
| Subdivision Name: |  Ecuador |
| Subdivision Type1: | Provinces |
| Subdivision Name1: | El Oro |
| Subdivision Type2: | Canton |
| Subdivision Name2: | Huaquillas |
| Parts Type: | Subdivisions |
| Parts Style: | para |
| Leader Title: | Mayor |
| Leader Name: | Florencio Farez |
| Unit Pref: | Metric |
| Area Total Km2: | 17.86 |
| Elevation M: | 10 |
| Population Footnotes: | [1] |
| Population Total: | 56021 |
| Population As Of: | 2022 census |
| Population Density Km2: | auto |
| Population Demonym: | Huaquillense |
| Timezone1: | ECT |
| Utc Offset1: | -5 |
| Website: | http://www.huaquillas.gob.ec/ |
Huaquillas (Spanish: /wa.'ki.ʝas/) is a border town in western El Oro, Ecuador. It is the canton seat of the Huaquillas Canton.
Huaquillas is located on the border with Peru. An international bridge that goes over the Zarumilla River connects it with the Peruvian town of Aguas Verdes. Both towns have an intense commercial life and many formal, as well as informal street sellers that sell goods both in US dollars, the only currency in Ecuador, and in Peruvian soles.
The town was occupied by Peru during the 1941 Ecuadorian–Peruvian War.
-3.4814°N -80.2432°W Puente Internacional Zarumilla, border crossing between Huaquillas and Aguas Verdes.