| Mohammad Hossein Sharifzadegan | |
| Term Start1: | 14 July 2004 |
| Term End1: | 24 August 2005 |
| President1: | Mohammad Khatami |
| Predecessor1: | Ministry established |
| Successor1: | Parviz Kazemi |
| Party: | Islamic Iran Participation Front |
| Birth Place: | Hamedan, Iran |
| Nationality: | Iranian |
| Relatives: | Mir-Hossein Mousavi [1] |
Mohammad Hossein Sharifzadegan (Persian: محمدحسین شریفزادگان) is an Iranian reformist politician. He served as the head of Social Security Organization for three years before taking office as a minister.