| Horrie Brain | |
| Fullname: | Horace Horton Brain |
| Birth Date: | 17 November 1885 |
| Birth Place: | Colebrook, Tasmania |
| Death Place: | Mount Nelson, Tasmania |
| Originalteam: | North Hobart |
| Statsend: | 1907 |
| Years1: | 1904–05 |
| Club1: | North Hobart |
| Years2: | 1906 |
| Club2: | Brisbane (QFL) |
| Years3: | 1907 |
| Games Goals3: | 11 (0) |
| Years4: | 1909–13 |
| Club4: | North Hobart |
Horace Horton Brain (17 November 1885 – 22 March 1966) was an Australian rules footballer who played with St Kilda in the Victorian Football League (VFL).
He later served in World War I, serving mainly in France and suffering mustard gas poisoning in 1917.[1]