Hopeaphenol Explained

Hopeaphenol is a stilbenoid. It is a resveratrol tetramer. It has been first isolated from Dipterocarpaceae^[1] like Shorea ovalis.^[2] It has also been isolated from wines from North Africa.^[3]

It shows an opposite effect to vitisin A on apoptosis of myocytes isolated from adult rat heart.^[4]

See also

• Phenolic compounds in wine

Notes and References

1. The structure of hopeaphenol. P. Coggon, T. J. King and S. C. Wallwork, Chem. Commun. (London), 1966, pages 439-440,
2. The Isolation of Hopeaphenol, a Tetramer Stilbene, from Shorea ovalis Blume. Advances in Natural & Applied Sciences, January–April 2009, Volume 3, Issue 1, page 107 (abstract)
3. Hopeaphenol: The First Resveratrol Tetramer in Wines from North Africa . Habiba Amira Guebailia . Kleopatra Chira . Tristan Richard . Teguiche Mabrouk . Aurélie Furiga . Xavier Vitrac . Jean-Pierre Monti . Jean-Claude Delaunay . Jean-Michel Mérillon . J. Agric. Food Chem. . 2006 . 54 . 9559–9564 . 10.1021/jf062024g . 25 . 17147446.
4. Seya . Kazuhiko . Kanemaru . Kouta . Sugimoto . Chiharu . Suzuki . Megumi . Takeo . Teruko . Motomura . Shigeru . Kitahara . Haruo . Niwa . Masatake . Oshima . Yoshiteru . Furukawa . Ken-Ichi . 5. Opposite Effects of Two Resveratrol (trans-3,5,4′-Trihydroxystilbene) Tetramers, Vitisin A and Hopeaphenol, on Apoptosis of Myocytes Isolated from Adult Rat Heart . Journal of Pharmacology and Experimental Therapeutics . American Society for Pharmacology & Experimental Therapeutics (ASPET) . 328 . 1 . 2008-10-16 . 0022-3565 . 10.1124/jpet.108.143172 . 90–98. 18927354 . 22844861 .