Hopantenic acid explained

Hopantenic acid (homopantothenic acid), also known as N-pantoyl-GABA, is a central nervous system depressant. Formulated as the calcium salt, it is used as a pharmaceutical drug in the Russian Federation for a variety of neurological, psychological and psychiatric conditions and sold as Pantogam (Russian: Пантогам).[1]

Chemistry

Hopantenic acid is a homologue of pantothenic acid. While pantothenic acid is the amide of D-pantoate and β-alanine, hopantenic acid is the amide of D-pantoate and γ-aminobutyric acid (GABA). This change leads to an additional CH2 in the molecule.[2]

See also

External links

Notes and References

  1. Web site: Hopantenic acid . 2023-09-18 . DrugBank.
  2. Kopelevich VM, Evdokimova GS, Marieva TD, Shmuilovich LM. Synthesis of D-homopantothenic acid . Pharmaceutical Chemistry Journal . 5 . 9 . 1971 . 534–536. 10.1007/BF00771659. 33296093 .