Homochlorcyclizine Explained

Homochlorcyclizine (INN) is an antihistamine of the diphenylmethylpiperazine group which has been marketed in Japan since 1965.[1] It is used in the treatment of allergies and other conditions. It also has some anticholinergic, antidopaminergic, and antiserotonergic properties.[2] [3]

See also

Notes and References

  1. Web site: Homoclomin Tablets 10 mg . December 2007 . . 2008-07-29.
  2. Haraguchi K, Ito K, Kotaki H, Sawada Y, Iga T . Prediction of drug-induced catalepsy based on dopamine D1, D2, and muscarinic acetylcholine receptor occupancies . Drug Metabolism and Disposition . 25 . 6 . 675–84 . June 1997 . 9193868 .
  3. KIMURA ET, YOUNG PR, RICHARDS RK . Pharmacologic properties of N-p-chloro-benzhydryl-N'-methyl homopiperazine dihydrochloride (homochlorcyclizine; SA-97), a serotonin antagonist . Journal of Allergy . 31 . 237–47 . 1960 . 10.1016/0021-8707(60)90052-6 . 14409112 .

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