| Country: | England |
| Coordinates: | 52.07°N -0.262°W |
| Official Name: | Holme |
| Civil Parish: | Biggleswade |
| Unitary England: | Central Bedfordshire |
| Lieutenancy England: | Bedfordshire |
| Region: | East of England |
| Constituency Westminster: | North East Bedfordshire |
| Post Town: | BIGGLESWADE |
| Postcode District: | SG18 |
| Postcode Area: | SG |
| Dial Code: | 01767 |
| Os Grid Reference: | TL192427 |
Holme is a hamlet in the civil parish of Biggleswade, in the Central Bedfordshire district of Bedfordshire, England.
The settlement is close to Edworth and Langford. The nearest town to Holme is Biggleswade.