Holly Brown-Borg Explained

Holly Brown-Borg is an American biologist and biogerontologist best known for her research on the regulation of lifespan by growth hormone. She is the Chester Fritz Distinguished Professor of Pharmacology, Physiology & Therapeutics at the University of North Dakota School of Medicine and Health Sciences.

Education and training

Brown-Borg attended the University of Nebraska-Lincoln as an undergraduate, receiving a B.S. in Agriculture and an M.S. in Animal Science.[1] [2] She performed her Ph.D. research at North Carolina State University, followed by post-doctoral research at the USDA Meat Animal Research Center and Southern Illinois University.[3]

Academic career

Brown-Borg joined the faculty of the University of North Dakota School of Medicine and Health Sciences in the Department of Pharmacology, Physiology & Therapeutics as an Assistant Professor in 1995 and was tenured as Associate Professor in 2002. In 2010, Brown-Borg was selected as a Chester Fritz Distinguished Professor, an endowed professorship established by Chester Fritz.[4] [5] She has received several awards for her work, including an Ellison Medical Foundation Senior Scholar Award and the Glenn Award for Research in Biological Mechanisms of Aging. Her contributions to the field of the biology of aging were recognized in 2013 by receipt of the Denham Harman Lifetime Achievement Research Award from the American Aging Association, the society's highest honor.

Brown-Borg is a leader in the field of aging. In 2010 served as president of the American Aging Association; she also has served as Chair of Biological Sciences section of Gerontological Society of America. Her contribution to aging and these societies have been recognized by her election as a Fellow of the Gerontological Society of America in 2006 and a Fellow of the American Aging Association in 2016.

In postdoctoral research completed by Brown-Borg in Andrzej Bartke's laboratory, Brown-Borg demonstrated that the Ames Dwarf mouse had a significant increase in lifespan.[6] [7] Brown-Borg's work has also linked growth hormone signaling to oxidative stress and methionine metabolism,[8] [9] [10] and highlighted the role of growth hormone in the pro-longevity effects of methionine restriction.[11]

Honors and awards

Professional societies

References

  1. Web site: Holly Brown-Borg, Ph.D. Faculty Staff Archive Biomedical Sciences School of Medicine & Health Sciences UND: University of North Dakota. Dakota. - The University of North. www.med.und.edu. en-US. 2017-08-24.
  2. Web site: Lifeboat Foundation Bios: Professor Holly M. Brown-Borg. lifeboat.com. 2017-08-24.
  3. Web site: Brown-Borg, Holly PhD – #OW2017 ObesityWeek 2017. obesityweek.com. en-US. 2017-08-24.
  4. Web site: Chester Fritz Distinguished Professors Provost UND: University of North Dakota. Dakota. - The University of North. und.edu. en-US. 2017-08-24.
  5. Web site: Holly Brown-Borg Faculty UND: University of North Dakota. Dakota. - The University of North. und.edu. en-US. 2017-08-24.
  6. Book: Stipp, David. The Youth Pill: Scientists at the Brink of an Anti-Aging Revolution. 2010-07-08. Penguin. 9781101442289. en.
  7. Brown-Borg. H. M.. Borg. K. E.. Meliska. C. J.. Bartke. A.. 1996-11-07. Dwarf mice and the ageing process. Nature. 384. 6604. 33. 10.1038/384033a0. 0028-0836. 8900272. 1996Natur.384...33B . 4327014. free.
  8. Brown-Borg. Holly M.. Rakoczy. Sharlene G.. Wonderlich. Joseph A.. Rojanathammanee. Lalida. Kopchick. John J.. Armstrong. Vanessa. Raasakka. Debbie. December 2014. Growth hormone signaling is necessary for lifespan extension by dietary methionine. Aging Cell. 13. 6. 1019–1027. 10.1111/acel.12269. 1474-9726. 4244257. 25234161.
  9. Brown-Borg. Holly M.. Rakoczy. Sharlene G.. Uthus. Eric O.. March 2005. Growth hormone alters methionine and glutathione metabolism in Ames dwarf mice. Mechanisms of Ageing and Development. 126. 3. 389–398. 10.1016/j.mad.2004.09.005. 0047-6374. 15664625. 25155125.
  10. Brown-Borg. Holly M.. Rakoczy. Sharlene G.. December 2003. Growth hormone administration to long-living dwarf mice alters multiple components of the antioxidative defense system. Mechanisms of Ageing and Development. 124. 10–12. 1013–1024. 0047-6374. 14659590. 10.1016/j.mad.2003.07.001. 22539005.
  11. Web site: Growth Hormone Guidance. The Scientist. 2017-08-24.
  12. Web site: American Aging Association - Fellows. www.americanagingassociation.org. en. 2017-11-18.
  13. Web site: UND researcher Holly Brown-Borg honored with Lifetime Achievement Award 06 2013 News School of Medicine & Health Sciences UND: University of North Dakota. Dakota. - The University of North. www.med.und.edu. en-US. 2017-08-24.
  14. News: HIGHER EDUCATION NOTES: UND committee for new med school. 2017-11-18. en.
  15. Web site: 2014 Scientific Committees. AFAR. 2017-08-24.
  16. Web site: 2103 Scientific Committees. AFAR. 2017-08-24.
  17. Web site: 2011 Scientific Committees. AFAR. 2017-08-24.
  18. Web site: Glenn Foundation for Medical Research Glenn Award for Research in Biological Mechanisms of Aging. glennfoundation.org. en-US. 2017-11-18.
  19. Web site: American Aging Association - Organization. www.americanagingassociation.org. en. 2017-11-18.
  20. Web site: Gerontology News. July 2009. The Gerontological Society of America. November 18, 2017.
  21. Web site: 'Manna from Heaven': Holly Brown-Borg Receives an Unsolicited Award to Support Research on Aging in Ames Dwarf Mice. www.newswise.com. 2017-08-24.

External links

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