Holin LLH family explained

The holin LLH family (TC# 1.E.26) is a group of transporters belonging to the Holin superfamily VI.^[1] The Holin LLH family is found in Bacillota and phage of Bacillota as well as other bacteria. Members are fairly large, between 100 and 160 amino acyl residues in length, and have an N-terminal transmembrane segment (TMS). Some proteins, such as putative holin of Fusobacterium varium (TC# 1.E.26.7.2), may exhibit 2 TMSs. A representative list of proteins belonging to the Holin LLH family can be found in the Transporter Classification Database.^{[2] [3]}

See also

• Holin/Holin Superfamilies
• Lysin
• Transporter Classification Database

Further reading

• 10077848 . 171 . Molecular analysis of the region encoding the lytic system from Oenococcus oeni temperate bacteriophage phi 10MC . 1999 . FEMS Microbiol Lett . 231–8 . Gindreau . E . Lonvaud-Funel . A . 2 . 10.1016/s0378-1097(99)00006-3.
• 17711456 . 10.1111/j.1574-6968.2007.00873.x . 275 . Genome sequence of Streptococcus mutans bacteriophage M102 . 2007 . FEMS Microbiol Lett . 130–8 . van der Ploeg . JR. 1 . free .
• 19120640 . 10.1111/j.1365-2672.2008.03953.x . 105 . Identification and characterization of the two-component cell lysis cassette encoded by temperate bacteriophage phiPYB5 of Lactobacillus fermentum . 2008 . J Appl Microbiol . 1939–44 . Wang . S . Kong . J . Zhang . X. 6 . 25967192 . free .

Notes and References

1. Reddy. Bhaskara L.. Saier Jr.. Milton H.. 2013-11-01. Topological and phylogenetic analyses of bacterial holin families and superfamilies. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1828. 11. 2654–2671. 10.1016/j.bbamem.2013.07.004. 3788059. 23856191.
2. Web site: 1.E.26 The Holin LLH (Holin LLH) Family. Transporter Classification Database. 2016-03-21.
3. http://www.tcdb.org/search/result.php?tc=1.E.26.9 Transporter Classification Database