The Holburn Baronetcy, of Menstrie in the County of Clackmannan, was a title in the Baronetage of Nova Scotia. It was created on 21 June 1706 for James Holburn who was later titled, Sir James Holburn, 1st Baronet. He was the son of Major General Sir James Holborne of Menstrie. The third Baronet was a captain in the Royal Navy. The fifth Baronet was founder of the Holburne Museum of Art, Bath, Somerset. On his death in 1874 the baronetcy became either extinct or dormant.
The family seat was Menstrie Castle, Menstrie, Clackmannanshire.