| Country: | ISR |
| Type: | Hwy |
| Route: | 42 |
| Map Custom: | yes |
| Length Km: | 19 |
| Direction A: | North |
| Terminus A: | Ashdod Junction |
| Direction B: | South |
| Terminus B: | Gan Rave Junction |
| Previous Route: | 41 |
| Previous Type: | Hwy |
| Next Route: | 44 |
| Next Type: | Hwy |
Highway 42 is a north-south highway in central Israel. It leads from just south of Ashdod Interchange in the south to Gan Rave interchange in the north. The road is 19km (12miles) long.