Hexose oxidase explained

hexose oxidase
Ec Number:	1.1.3.5
Cas Number:	9028-75-5
Go Code:	0047979

In enzymology, a hexose oxidase is an enzyme that catalyzes the chemical reaction

D-glucose + O₂

\rightleftharpoons D-glucono-1,5-lactone + H₂O₂

Thus, the two substrates of this enzyme are D-glucose and O₂, whereas its two products are D-glucono-1,5-lactone and H₂O₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. The systematic name of this enzyme class is D-hexose:oxygen 1-oxidoreductase. This enzyme participates in pentose phosphate pathway. It employs one cofactor, copper.

References

• BEAN RC, HASSID WZ . 1956 . Carbohydrate oxidase from A red alga, Iridophycus flaccidum . J. Biol. Chem. . 218 . 425 - 36 . 13278350 . 1 .
• BEAN RC, PORTER GG, STEINBERG BM . 1961 . Carbohydrate metabolism of citrus fruits. II. Oxidation of sugars by an aerodehydrogenase from young orange fruits . J. Biol. Chem. . 236 . 1235 - 40 . 13688220 .
• Sullivan JD, Ikawa M . 1973 . Purification and characterization of hexose oxidase from the red alga Chondrus crispus . Biochim. Biophys. Acta . 309 . 11 - 22 . 4708670 . 1 . 10.1016/0005-2744(73)90312-4.