Hericenone Explained

thumb|Hericenone C-HHericenones is a class of benzaldehydes that are isolates of the fruiting body of Hericium erinaceum (lion's mane mushroom) that promote nerve growth factor synthesis in vitro.[1] [2]

Hericenones

Hericenones! Name!!IUPAC name !! Reference
Hericenone A 5-[(2E)-3,7-dimethyl-5-oxoocta-2,6-dienyl]-4-hydroxy-6-methoxy-3H-2-benzofuran-1-one[3] [4]
Hericenone B 6-[(2Z)-3,7-dimethyl-5-oxoocta-2,6-dienyl]-7-hydroxy-5-methoxy-2-(2-phenylethyl)-3H-isoindol-1-one[5]
Hericenone C [4-[(2E)-3,7-dimethyl-5-oxoocta-2,6-dienyl]-2-formyl-3-hydroxy-5-methoxyphenyl]methyl hexadecanoate[6] [7]
Hericenone D [4-[(2E)-3,7-dimethyl-5-oxoocta-2,6-dienyl]-2-formyl-3-hydroxy-5-methoxyphenyl]methyl octadecanoate[8]
Hericenone E [4-[(2E)-3,7-dimethyl-5-oxoocta-2,6-dienyl]-2-formyl-3-hydroxy-5-methoxyphenyl]methyl (9E,12E)-octadeca-9,12-dienoate
Hericenone F [8-formyl-5-methoxy-2-methyl-2-(4-methyl-2-oxopent-3-enyl)-3,4-dihydrochromen-7-yl]methyl hexadecanoate[9] [10]
Hericenone G [8-formyl-5-methoxy-2-methyl-2-(4-methyl-2-oxopent-3-enyl)-3,4-dihydrochromen-7-yl]methyl octadecanoate[11]
Hericenone H [8-formyl-5-methoxy-2-methyl-2-(4-methyl-2-oxopent-3-enyl)-3,4-dihydrochromen-7-yl]methyl (9E,12E)-octadeca-9,12-dienoate[12]
Hericenone I
Hericenone J 6-[(2E)-3,7-dimethylocta-2,6-dienyl]-7-hydroxy-5-methoxy-3H-2-benzofuran-1-one[13]
Hericenone K 2-(4-hydroxy-4-methyl-2-oxopentyl)-5-methoxy-2-methyl-4,7-dihydro-3H-furo[3,4-h]chromen-9-one[14]

Notes and References

  1. 10.1016/0031-9422(92)80127-Z . 32 . Chromans, hericenones F, G and H from the mushroom Hericium erinaceum . 1992 . Phytochemistry . 175–178 . Kawagishi . Hirokazu . Ando . Motoharu . Shinba . Kayoko . Sakamoto . Hideki . Yoshida . Satoshi . Ojima . Fumihiro . Ishiguro . Yukio . Ukai . Nobuo . Furukawa . Shoei.
  2. Ma . B-J . Shen . J-W . Yu . H-Y . Ruan . Yuan . Wu . T-T . Zhao . X . Jun 2010 . Hericenones and erinacines: stimulators of nerve growth factor (NGF) biosynthesis in Hericium erinaceus . Mycology . 1 . 2. 92–98 . 10.1080/21501201003735556. free .
  3. Web site: Hericenone A . PubChem . 2021-04-11.
  4. Hericenone A and B as cytotoxic principles from the mushroom hericium erinaceum . Tetrahedron Letters . 31 . 3 . 1990-01-01 . 0040-4039 . 10.1016/S0040-4039(00)94558-1 . 373–376 . 2021-04-11.
  5. Web site: Hericenone B . PubChem . 2021-04-11.
  6. Web site: Hericenone C . PubChem . 2021-04-11.
  7. Hericenones C, D and E, stimulators of nerve growth factor (NGF)-synthesis, from the mushroom Hericium erinaceum . Tetrahedron Letters . 32 . 35 . 1991-01-01 . 0040-4039 . 10.1016/0040-4039(91)80039-9 . 4561–4564 . 2021-04-11. Kawagishi . Hirokazu . Ando . Motoharu . Sakamoto . Hideki . Yoshida . Satoshi . Ojima . Fumihiro . Ishiguro . Yukio . Ukai . Nobuo . Furukawa . Shoei .
  8. Web site: Hericenone D . PubChem . 2021-04-11.
  9. Web site: Hericenone F . PubChem . 2021-04-11.
  10. Chromans, hericenones F, G and H from the mushroom Hericium erinaceum . Phytochemistry . 32 . 1 . 1992-12-23 . 0031-9422 . 10.1016/0031-9422(92)80127-Z . 175–178 . 2021-04-11. Kawagishi . Hirokazu . Ando . Motoharu . Shinba . Kayoko . Sakamoto . Hideki . Yoshida . Satoshi . Ojima . Fumihiro . Ishiguro . Yukio . Ukai . Nobuo . Furukawa . Shoei .
  11. Web site: Hericenone G . PubChem . 2021-04-11.
  12. Web site: Hericenone H . PubChem . 2021-04-11.
  13. Web site: Hericenone J . PubChem . 2021-04-12.
  14. Web site: Hericenone K . PubChem . 2021-04-12.

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