| Herb Appenzeller | |
| Birth Date: | 28 September 1925 |
| Death Place: | Greensboro, North Carolina, U.S. |
| Player Sport1: | Football |
| Player Years2: | 1944–1947 |
| Player Team2: | Wake Forest |
| Coach Sport1: | Football |
| Coach Years2: | 1948 |
| Coach Team2: | Rolesville HS (NC) |
| Coach Years3: | 1949–1950 |
| Coach Team3: | Wakelon HS (NC) |
| Coach Years4: | 1951–1955 |
| Coach Team4: | Chowan |
| Coach Years5: | 1956–1962 |
| Coach Team5: | Guilford |
| Coach Sport6: | Basketball |
| Coach Years8: | 1948–1949 |
| Coach Team8: | Rolesville HS (NC) |
| Admin Years1: | 1956–1987 |
| Admin Team1: | Guilford |
| Overall Record: | 10–50–1 (college football) |
Herbert Thomas Appenzeller (September 28, 1925 – January 5, 2018) was an American football coach and college athletics administrator.[1] He served as the head football coach at Guilford College in Greensboro, North Carolina from 1956 to 1962, compiling a record of 10–50–1.[2] A native of Newark, New Jersey, Appenzeller played college football and ran track at Wake Forest University. He was the head football coach at Chowan College—now known as Chowan University—in Murfreesboro, North Carolina from 1951 to 1955, when the school was a junior college.[3]