Hepatitis E virus cis-reactive element explained

Hepatitis E virus cis-reactive element
Symbol:HepE_CRE
Rfam:RF00550
Rna Type:Cis-reg
Tax Domain:Viruses

The hepatitis E virus cis-reactive element is an RNA element that is believed to be essential for "some step in gene expression".[1] The mutation of this element resulted in hepatitis E strains which were unable to infect rhesus macaques (Macaca mulatta).

Notes and References

  1. Graff J, Nguyen H, Yu C, Elkins WR, St Claire M, Purcell RH, Emerson SU . The open reading frame 3 gene of hepatitis E virus contains a cis-reactive element and encodes a protein required for infection of macaques . Journal of Virology . 79 . 11 . 6680–6689 . June 2005 . 15890906 . 1112134 . 10.1128/JVI.79.11.6680-6689.2005 .

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