| Henry O. Fairbanks | |
| Office: | Mayor of Quincy, Massachusetts |
| Term Start: | 1890 |
| Term End: | 1893 |
| Predecessor: | Charles H. Porter |
| Successor: | William A. Hodges |
| Office2: | President of the Quincy, Massachusetts Common Council |
| Office3: | Member of the Quincy, Massachusetts Common Council Ward 5 |
| Birth Date: | June 21, 1853 |
| Birth Place: | Boston, Massachusetts, US |
| Death Place: | Quincy, Massachusetts, US |
| Resting Place: | Jamaica Plain, Massachusetts |
| Party: | Republican |
| Alma Mater: | Boston English High School, 1869 |
| Profession: | Flour merchant |
Henry Orlestus Fairbanks (1852–1928) was the second mayor of Quincy, Massachusetts.