| Henry Killeen | |
| Position: | Pitcher |
| Birth Date: | May 1872 |
| Birth Place: | Troy, New York |
| Death Place: | Waterbury, Connecticut |
| Bats: | Unknown |
| Throws: | Unknown |
| Debutleague: | MLB |
| Debutdate: | September 11 |
| Debutyear: | 1891 |
| Debutteam: | Cleveland Spiders |
| Finalleague: | MLB |
| Finaldate: | September 11 |
| Finalyear: | 1891 |
| Finalteam: | Cleveland Spiders |
| Statleague: | MLB |
| Stat1label: | Win–loss record |
| Stat2label: | Earned run average |
| Stat3label: | Strikeouts |
| Stat1value: | 0-1 |
| Stat2value: | 6.23 |
| Stat3value: | 3 |
| Teams: | |
Henry F. Killeen (May 1872 – October 16, 1916) was a starting pitcher in Major League Baseball. He pitched in one game for the Cleveland Spiders of the National League on September 11, 1891. He remained active in the minor leagues through 1899.