| Henderson Run | |
| Name Other: | Tributary to Pine Creek |
| Map Size: | 300 |
| Map Alt: | Map of the mouth of Henderson Run |
| Pushpin Map: | Pennsylvania#USA |
| Pushpin Map Size: | 300 |
| Pushpin Map Alt: | Location of Henderson Run mouth |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | Pennsylvania |
| Subdivision Type3: | County |
| Subdivision Name3: | Crawford |
| Length: | 3.3miles[1] |
| Discharge1 Location: | Pine Creek |
| Discharge1 Avg: | 3.55cuft/s at mouth with Pine Creek[2] |
| Source1: | divide between Henderson Run and Porky Run |
| Source1 Location: | about 2 miles west of Dotyville, Pennsylvania |
| Source1 Coordinates: | 41.6672°N -79.6378°W[3] |
| Source1 Elevation: | 1620feet[4] |
| Mouth: | Pine Creek |
| Mouth Location: | about 1 mile northeast of East Titusville, Pennsylvania |
| Mouth Coordinates: | 41.6306°N -79.62°W |
| Mouth Elevation: | 1184feet |
| Progression: | south-southeast |
| River System: | Allegheny River (Oil Creek) |
| Tributaries Left: | unnamed tributaries |
| Tributaries Right: | unnamed tributaries |
| Bridges: | Spring Creek Road, Keyes Road |
Henderson Run is a 3.3miles long 1st order tributary to Pine Creek in Crawford County, Pennsylvania.
Henderson Run rises about 2 miles west of Dotyville, Pennsylvania in Crawford County and then flows south-southeast to Pine Creek about 1 mile northeast of East Titusville, Pennsylvania.[4]
Henderson Run drains of area, receives about 44.9 in/year of precipitation, and has a wetness index of 433.72 and is about 81% forested.[2]