Helional Explained

Helional (from heliotropin, from which is it commonly derived) is a chemical compound used as a perfume in soap and laundry detergent. Chemically it is an aldehyde with a hydrocinnamaldehyde motif; a structural element which is present in a number of other important commercial fragrances and odorants.[1]

Synthesis

Several synthetic routes exist but the most common is a crossed-aldol condensation between piperonal (heliotropin) and propanal followed by selective hydrogenation of the intermediate alkene. This produces a racemic product.

See also

Notes and References

  1. Specificity and sensitivity of a human olfactory receptor functionally expressed in human embryonic kidney 293 cells and Xenopus laevis oocytes. Wetzel, Christian H. . Oles, Markus . Wellerdieck, Christiane . Kuczkowiak, Michael . Gisselmann, Gunter . Hatt, Hanns . Journal of Neuroscience. 1999. 19. 1. 7426–7433. 10.1093/chemse/bji002. 15647465. free.