| Official Name: | Haute Matsiatra Region |
| Native Name: | Matsiatra Ambony |
| Settlement Type: | Region |
| Mapsize: | 180px |
| Subdivision Type: | Country |
| Seat Type: | Capital |
| Seat: | Fianarantsoa |
| Government Footnotes: | [1] |
| Leader Title: | Gouvernor |
| Leader Name: | Lova Narivelo Razafindrafito |
| Area Footnotes: | [2] |
| Area Total Km2: | 21080 |
| Population As Of: | 2018 |
| Population Footnotes: | [3] |
| Population Total: | 1447296 |
| Population Density Km2: | 53.5 |
| Population Blank1 Title: | Ethnicities |
| Population Blank2 Title: | Religions |
| Timezone: | EAT |
| Utc Offset: | 3 |
| Blank Name Sec1: | HDI (2018) |
| Blank Info Sec1: | 0.516[4] · 12th of 22 |
Haute Matsiatra (in Malagasy: Matsiatra Ambony) is a region in Madagascar. It borders Amoron'i Mania region in north, Vatovavy-Fitovinany in east, Ihorombe in south and Atsimo-Andrefana in west. The capital of the region is Fianarantsoa, and the population was 1,447,296 in 2018. The area is 210800NaN0.[3]
Matsiatra Ambony is the top wine producing region of Madagascar, with wineyards in Ambalavao, Famoriana and Isandra (district).In Sahambavy is found the only tea production of the country.
Haute Matsiatra Region is divided into seven districts, which are sub-divided into 84 communes.
The Fianarantsoa-Côte Est railway has its endpoint in Fianarantsoa. It leads to the east coast and Manakara.
The main river is the Matsiatra.