| Building Name: | Hatuniye Medresseh Hatuniye Medresesi |
| Location: | Karaman, Karaman Province, Turkey |
| Religious Affiliation: | Islam |
| Architecture: | yes |
| Architect: | Numanoğlu Hoca Ahmed |
| Architecture Type: | Civil |
| Architecture Style: | Islamic, Ottoman architecture |
| Year Completed: | c. 1382[1] |
Hatuniye Medresseh (Turkish: Hatuniye Medresesi), is a historical medrese in Karaman, Turkey, built in the 14th century. The like-named Hatuniye Külliyesi in Tokat is a century younger, and refers to another woman.
Ottoman Sultan Murat Hüdavendigar's daughter Sultan Hatun, wife of Karamanoğlu Alaattin Bey, ordered the construction in 1382. The architect of the Medrese is Numanoğlu Hoca Ahmed (Hodja Ahmed, son of Numan), according to the kitabe (inscription) of the building.[2]
The building is made of cut stone from around Karaman and the main gate (portal) from marble.[2]