Hartmut Wekerle Explained

Hartmut Wekerle
Birth Date:30 May 1944
Birth Place:Germany
Occupation:Medical Scientist, Neurobiologist
Alma Mater:Albert Ludwig University of Freiburg
Spouse:Rosa-Laura Oropeza Wekerle

Hartmut Wekerle (born 30 May 1944) is a German medical scientist and neurobiologist. He is an emeritus director at the Max Planck Institute of Neurobiology and was the head of the department of Neuroimmunology until 2012.

Biography

Hartmut Wekerle was born in Waldshut in 1944. He studied medicine at the University of Freiburg. In 1967, he began scientific research at the Max Planck Institute for Immunobiology in Freiburg as a PhD student under Herbert Fischer. He finished his doctorate in 1971. After graduation, he worked at the Weizmann Institute of Science from 1971 to 1973 as a postdoctorate researcher. Later on, he led the Research Group for Multiple Sclerosis at the Institute of Clinical Neurobiology at the University Hospital of the University of Würzburg. In 1988, he was appointed director at the Max Planck Institute of Neurobiology (now Max Planck Institute for Biological Intelligence[1]). After receiving the Emeritus status at the institute in 2012, he continued his research for another five years as a Senior Professorship funded by the Hertie Foundation.

Scientific focus

Hartmut Wekerle's work has been devoted to the study of cellular immune responses and mechanisms in the course of multiple sclerosis and other inflammatory diseases in the nervous system.

In particular, his research contributed to the following discoveries:

Awards (Selection)

Honorary Degrees and Memberships

Notes and References

  1. Web site: New Max Planck Institute for Biological Intelligence, in foundation . 2022-04-20.
  2. Wekerle. H. Cohen. IR. Feldman. M. Thymus reticulum cell cultures confer T cell properties on spleen cells from thymus-deprived animals . Eur J Immunol . 3 . 12 . 745–8 . December 1973 . 4544457 . 10.1002/eji.1830031202 . 44482733. en.
  3. Fontana . A . Fierz . W . Wekerle . H . Astrocytes present myelin basic protein to encephalitogenic T-cell lines . Nature . 307 . 5948 . 273–6 . 1984 . 6198590 . 10.1038/307273a0 . 1984Natur.307..273F . 2468077 . en.
  4. Sun . D . Qin . Y . Chluba . J . Epplen . JT . Wekerle . H . Suppression of experimentally induced autoimmune encephalomyelitis by cytolytic T-T cell interactions . Nature . 332 . 6167 . 843–5 . April 1988 . 2965794 . 10.1038/332843a0 . 1988Natur.332..843S . 4307955 . en.
  5. Neumann . H . Cavalié . A . Jenne . DE . Wekerle . H . Induction of MHC class I genes in neurons . Science . 269 . 5223 . 549–52 . July 1995 . 7624779 . 10.1126/science.7624779 . 1995Sci...269..549N . en.
  6. Bartholomäus . I . Kawakami . N . Odoardi . F . Schläger . C . Miljkovic . D . Ellwart . JW . Klinkert . WE . Flügel-Koch . C . Issekutz . TB . Wekerle . H . Flügel . A . Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions . Nature . 462 . 7269 . 94–8 . November 2009 . 19829296 . 10.1038/nature08478 . 2009Natur.462...94B . 4373646 . en.
  7. Berer . K . Mues . M . Koutrolos . M . Rasbi . ZA . Boziki . M . Johner . C . Wekerle . H . Krishnamoorthy . G . Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination . Nature . 479 . 7374 . 538–41 . October 2011 . 22031325 . 10.1038/nature10554 . 2011Natur.479..538B . 12678288 . en.
  8. Berer . K . Gerdes . LA . Cekanaviciute . E . Jia . X . Xiao . L . Xia . Z . Liu . C . Klotz . L . Stauffer . U . Baranzini . SE . Kümpfel . T . Hohlfeld . R . Krishnamoorthy . G . Wekerle . H . Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice . Proc Natl Acad Sci U S A . 114 . 40 . 10719–10724 . October 2017 . 28893994 . 5635914 . 10.1073/pnas.1711233114 . 2017PNAS..11410719B . en. free .
  9. Web site: Preisträger 1976 bis 2019. Jung-Stiftung für Wissenschaft und Forschung. 2022-05-02. 2022-01-27. https://web.archive.org/web/20220127122506/https://jung-stiftung.de/die-preise/ernst-jung-preis-fuer-medizin/preistraeger-1976-bis-2019/. dead.
  10. Web site: Auszeichnung für neurologische Grundlagenforschung. Max-Planck-Gesellschaft. 2022-05-02.
  11. Web site: Charcot Award winners. Multiple Sclerosis International Federation. 2022-05-02.
  12. Web site: Fondation Louis D.. 25 March 2013. l'Institut de France. 2022-05-02.
  13. Web site: Former Awardees. Betty & David Koetser Foundation for Brain Research. 2022-05-02.
  14. Web site: Jacob-Henle-Medaille. Universitätsmedizin Göttingen. 2022-05-02.