| Harry Lightsey | |
| Birth Date: | 3 February 1901 |
| Birth Place: | Brunson, South Carolina, U.S. |
| Death Place: | Columbia, South Carolina, U.S. |
| Player Years1: | 1919–1922 |
| Player Team1: | South Carolina |
| Player Positions: | Guard |
| Coach Years1: | 1923–1926 |
| Coach Team1: | Columbia HS (SC) |
| Coach Years2: | 1927 |
| Coach Team2: | South Carolina |
| Overall Record: | 4–5 (college) |
| Championships: | 3 South Carolina State HS |
Harry McKinley Lightsey Sr. (February 3, 1901 – February 24, 1986) was an American college football player and coach, politician, and judge. He served as the head football coach at the University of South Carolina in Columbia, South Carolina in 1927, compiling a record of 4–5.[1]