Harriet Mayanja-Kizza Explained

Harriet Mayanja-Kizza
Birth Place:Uganda
Alma Mater:Makerere University


Case Western Reserve University

American College of Physicians
Years Active:1978–present
Nationality:Ugandan
Citizenship:Uganda
Former Dean
Makerere University School of Medicine

Harriet Mayanja-Kizza, MBChB, MMed, MSc, FACP, is a Ugandan physician, researcher, and academic administrator. She is the former Dean of Makerere University School of Medicine,[1] [2] the oldest medical school in East Africa,[3] established in 1924.[4]

Background and education

She was born in the Central Region of Uganda in the 1950s. She holds the degree of Bachelor of Medicine and Bachelor of Surgery, obtained from Makerere University in 1978. She also holds the degree of Master of Medicine in Internal Medicine, obtained in 1983, also from Makerere. She studied immunology and pathology at Case Western Reserve University in Cleveland, Ohio, USA, graduating with the degree of Master of Science in those fields in 1999.[2] She is a Fellow of the American College of Physicians.[5]

Career

Mayanja-Kizza has worked as a lecturer in the Department of Internal Medicine at Makerere University Medical School. She has also served as the head of the Department of Internal Medicine, both at the medical school and at Mulago National Referral Hospital, the university's teaching hospital. In November 2010, she was appointed dean of the Makerere Medical School, at Makerere University College of Health Sciences.[5] [6] She has presented widely at national, regional, and International conferences and has published extensively in peer journals.[7] In 2022, she was ranked by the AD Scientific Index as the best scientist in Uganda.[8] [9] [10]

Other considerations

Her area of specialization is immunology, focusing on the interaction between AIDS and tuberculosis. Her research studies, are in the areas of immunopathogenesis, and immune-modulation treatments among patients with human immunodeficiency virus infection and tuberculosis.[2] Professor Harriet Mayanja-Kizza is a Fellow of the Uganda National Academy of Sciences.[11]

See also

Research

She is a respected researcher with more than 200 publications and 9277 citations of her works as of May 2022.[12] Some of her articles with more than 100 citations include; A blood RNA signature for tuberculosis disease risk: a prospective cohort study (2016),[13] Outcomes of cryptococcal meningitis in Uganda before and after the availability of highly active antiretroviral therapy (2008),[14] A study of the safety, immunology, virology, and microbiology of adjunctive etanercept in HIV-1-associated tuberculosis (2004),[15] Impact of tuberculosis (TB) on HIV-1 activity in dually infected patients (2001),[16] Patient and health service delay in pulmonary tuberculosis patients attending a referral hospital: a cross-sectional study (2005),[17] Predictors of long-term viral failure among Ugandan children and adults treated with antiretroviral therapy (2007),[18] Four-gene pan-African blood signature predicts progression to tuberculosis (2018),[19] Sero-prevalence and risk factors for hepatitis B virus infection among health care workers in a tertiary hospital in Uganda (2010),[20] Novel serologic biomarkers provide accurate estimates of recent Plasmodium falciparum exposure for individuals and communities (2015),[21] Immunoadjuvant prednisolone therapy for HIV-associated tuberculosis: a phase 2 clinical trial in Uganda (2005),[22] Combination therapy with fluconazole and flucytosine for cryptococcal meningitis in Ugandan patients with AIDS (1998),[23] Severe sepsis in two Ugandan hospitals: a prospective observational study of management and outcomes in a predominantly HIV-1 infected population (2009),[24] Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection (2018),[25] IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure (2019),[26] Genome scan of M. tuberculosis infection and disease in Ugandans (2008),[27] Acceptance of routine testing for HIV among adult patients at the medical emergency unit at a national referral hospital in Kampala, Uganda (2007),[28] Diagnostic performance of a seven-marker serum protein biosignature for the diagnosis of active TB disease in African primary healthcare clinic attendees with signs and symptoms suggestive of TB (2016),[29] The impact of early monitored management on survival in hospitalized adult Ugandan patients with severe sepsis: a prospective intervention study (2012),[30] High T-cell immune activation and immune exhaustion among individuals with suboptimal CD4 recovery after 4 years of antiretroviral therapy in an African cohort (2011),[31] FCRL5 Delineates Functionally Impaired Memory B Cells Associated with Plasmodium falciparum Exposure (2015),[32] Concise gene signature for point‐of‐care classification of tuberculosis (2016), Relationship of immunodiagnostic assays for tuberculosis and numbers of circulating CD4+ T-cells in HIV infection (2010)[33]

Notes and References

  1. Web site: Accordia's Academic Alliance: Harriet Mayanja-Kizza, MBChB, MMed, MSc . 26 December 2014 . Accordia Foundation . dead . https://web.archive.org/web/20141226184404/http://www.accordiafoundation.org/what-we-do/infectious-diseases-institute-uganda/ugandan-academic-alliance/index.html#Mayanja-Kizza . 26 December 2014 .
  2. Web site: Profile of Professor Harriet Mayanja-Kizza; Dean, School of Medicine at Makerere University College of Health Sciences . 3 December 2014 . 4 November 2016 . Uganda Campus Times . Kampala.
  3. Web site: 27 December 2014. Uganda Virus Research Institute: Our Partners. 11 April 2014. Uganda Virus Research Institute. Entebbe. 27 December 2014. https://web.archive.org/web/20141227082301/http://www.uvri.go.ug/index.php/about-uvri/our-partners. dead.
  4. Web site: 26 December 2014 . Makerere University Medical School Was Founded In 1924 . https://web.archive.org/web/20141209185747/http://www.cumc.columbia.edu/dept/msih//ps/Uganda.html . dead . 9 December 2014 . 26 December 2014 . Columbia University Medical College (CUMC).
  5. Web site: 26 December 2014 . 27 May 2011 . 2011 Sub-Saharan Africa CFAR Conference: Speaker Bio - Harriet Mayanja-Kizza, MBChB, MMed, MSc, FACP . . dead . https://web.archive.org/web/20150605022246/http://cfar.ucsf.edu/cfar?page=symposia-11-mayanja-kizza . 5 June 2015 .
  6. Web site: 26 December 2014 . Academic Profile of Professor Harriet Mayanja-Kizza . . 5 November 2016 . https://web.archive.org/web/20161105032951/https://www.idi-makerere.com/board-members/harriet-mayanja-kizza . dead .
  7. Web site: In Depth Review Professor Harriet Mayanja-Kizza's Work . 26 December 2014 . 2009 . . dead . https://web.archive.org/web/20141226200347/http://www.cidri.uct.ac.za/isab/isab6.html . 26 December 2014 .
  8. Web site: Reporter . C. B. . 2022-05-17 . Makerere Has the Best Scientists in the Country - Report . 2022-07-09 . Campus Bee . en-US.
  9. Web site: Harriet Mayanja-Kizza - AD Scientific Index 2022 . 2022-07-09 . www.adscientificindex.com.
  10. Web site: admin . 2022-05-19 . Who are Uganda's Top 500 Scientists of 2022? A new report finds out . 2022-07-09 . MediaScape News . en-US . 2024-04-30 . https://web.archive.org/web/20240430144553/https://mediascapenews.com/2022/05/who-are-ugandas-top-500-scientists-of-2022-a-new-report-finds-out/ . dead .
  11. Web site: 26 December 2014 . UNAS: Fellow Profile . Uganda National Academy of Science . https://web.archive.org/web/20150302002902/http://ugandanationalacademy.org/fellow_profile.php . 2 March 2015 . dead .
  12. Web site: Harriet Mayanja-Kizza . 2022-05-22 . scholar.google.com.
  13. Zak . Daniel E . Penn-Nicholson . Adam . Scriba . Thomas J . Thompson . Ethan . Suliman . Sara . Amon . Lynn M . Mahomed . Hassan . Erasmus . Mzwandile . Whatney . Wendy . Hussey . Gregory D . Abrahams . Deborah . 2016-06-04 . A blood RNA signature for tuberculosis disease risk: a prospective cohort study . The Lancet . en . 387 . 10035 . 2312–2322 . 10.1016/S0140-6736(15)01316-1 . 27017310 . 5392204 . 53393545 . 0140-6736.
  14. Kambugu . Andrew . Meya . David B. . Rhein . Joshua . O'Brien . Meagan . Janoff . Edward N. . Ronald . Allan R. . Kamya . Moses R. . Mayanja-Kizza . Harriet . Sande . Merle A. . Bohjanen . Paul R. . Boulware . David R. . 2008-06-01 . Outcomes of Cryptococcal Meningitis in Uganda Before and After the Availability of Highly Active Antiretroviral Therapy . Clinical Infectious Diseases . 46 . 11 . 1694–1701 . 10.1086/587667 . 18433339 . 2593910 . 1058-4838.
  15. Wallis . Robert S. . Kyambadde . Peter . Johnson . John L. . Horter . Libby . Kittle . Rodney . Pohle . Monika . Ducar . Constance . Millard . Monica . Mayanja-Kizza . Harriet . Whalen . Christopher . Okwera . Alphonse . 2004-01-23 . A study of the safety, immunology, virology, and microbiology of adjunctive etanercept in HIV-1-associated tuberculosis . AIDS . 18 . 2 . 257–264 . 10.1097/00002030-200401230-00015 . 0269-9370 . 15075543. 17623568 . free .
  16. Toossi . Z . Mayanja-Kizza . H . Hirsch . C S . Edmonds . K L . Spahlinger . T . Hom . D L . Aung . H . Mugyenyi . P . Ellner . J J . Whalen . C W . 2001-02-01 . Impact of tuberculosis (TB) on HIV-1 activity in dually infected patients . Clinical and Experimental Immunology . 123 . 2 . 233–238 . 10.1046/j.1365-2249.2001.01401.x . 11207653 . 1905977 . 0009-9104.
  17. Kiwuwa . Mpungu S. . Charles . Karamagi . Harriet . Mayanja Kizza . 2005-11-24 . Patient and health service delay in pulmonary tuberculosis patients attending a referral hospital: a cross-sectional study . BMC Public Health . 5 . 1 . 122 . 10.1186/1471-2458-5-122 . 1471-2458 . 1310609 . 16307685 . free .
  18. Kamya . Moses R. . Mayanja-Kizza . Harriet . Kambugu . Andrew . Bakeera-Kitaka . Sabrina . Semitala . Fred . Mwebaze-Songa . Patricia . Castelnuovo . Barbara . Schaefer . Petra . Spacek . Lisa A. . Gasasira . Anne F. . Katabira . Elly . 2007-10-01 . Predictors of long-term viral failure among ugandan children and adults treated with antiretroviral therapy . Journal of Acquired Immune Deficiency Syndromes . 46 . 2 . 187–193 . 10.1097/QAI.0b013e31814278c0 . 1525-4135 . 17693883. 41634539 . free .
  19. Suliman . Sara . Thompson . Ethan G. . Sutherland . Jayne . Weiner . January . Ota . Martin O. C. . Shankar . Smitha . Penn-Nicholson . Adam . Thiel . Bonnie . Erasmus . Mzwandile . Maertzdorf . Jeroen . Duffy . Fergal J. . 2018-05-01 . Four-Gene Pan-African Blood Signature Predicts Progression to Tuberculosis . American Journal of Respiratory and Critical Care Medicine . 197 . 9 . 1198–1208 . 10.1164/rccm.201711-2340OC . 1073-449X . 6019933 . 29624071.
  20. Ziraba . Abdhalah K. . Bwogi . Josephine . Namale . Alice . Wainaina . Caroline W. . Mayanja-Kizza . Harriet . 2010-06-29 . Sero-prevalence and risk factors for hepatitis B virus infection among health care workers in a tertiary hospital in Uganda . BMC Infectious Diseases . 10 . 1 . 191 . 10.1186/1471-2334-10-191 . 1471-2334 . 2910699 . 20587047 . free .
  21. Helb . Danica A. . Tetteh . Kevin K. A. . Felgner . Philip L. . Skinner . Jeff . Hubbard . Alan . Arinaitwe . Emmanuel . Mayanja-Kizza . Harriet . Ssewanyana . Isaac . Kamya . Moses R. . Beeson . James G. . Tappero . Jordan . 2015-08-11 . Novel serologic biomarkers provide accurate estimates of recent Plasmodium falciparum exposure for individuals and communities . Proceedings of the National Academy of Sciences of the United States of America . 112 . 32 . E4438–4447 . 10.1073/pnas.1501705112 . 1091-6490 . 4538641 . 26216993. 2015PNAS..112E4438H . free .
  22. Mayanja-Kizza . Harriet . Jones-Lopez . Edward . Okwera . Alphonse . Wallis . Robert S. . Ellner . Jerrold J. . Mugerwa . Roy D. . Uganda–Case Western Research Collaboration . 2005-03-15 . Immunoadjuvant Prednisolone Therapy for HIV-Associated Tuberculosis: A Phase 2 Clinical Trial in Uganda . The Journal of Infectious Diseases . 191 . 6 . 856–865 . 10.1086/427995 . 15717259 . 4515766 . 0022-1899.
  23. Kizza . Harriet Mayanja . Oishi . Kazunori . Mitarai . Satoshi . Yamashita . Hiroshi . Nalongo . Kisembo . Watanabe . Kiwao . Izumi . Takashi . Jungala . Ococi . Augustine . Kaddhu . Mugerwa . Roy . Nagatake . Tsuyoshi . 1998-06-01 . Combination Therapy with Fluconazole and Flucytosine for Cryptococcal Meningitis in Ugandan Patients with AIDS . Clinical Infectious Diseases . 26 . 6 . 1362–1366 . 10.1086/516372 . 9636863 . 1058-4838.
  24. Jacob . Shevin T. . Moore . Christopher C. . Banura . Patrick . Pinkerton . Relana . Meya . David . Opendi . Pius . Reynolds . Steven J. . Kenya-Mugisha . Nathan . Mayanja-Kizza . Harriet . Scheld . W. Michael . Group¶ . for the Promoting Resource-limited Interventions for Sepsis Management in Uganda (PRISM-U) Study . 2009-11-11 . Severe Sepsis in Two Ugandan Hospitals: a Prospective Observational Study of Management and Outcomes in a Predominantly HIV-1 Infected Population . PLOS ONE . en . 4 . 11 . e7782 . 10.1371/journal.pone.0007782 . 1932-6203 . 2771355 . 19907656. 2009PLoSO...4.7782J . free .
  25. Simmons . Jason D . Stein . Catherine M . Seshadri . Chetan . Campo . Monica . Alter . Galit . Galit Alter . Fortune . Sarah . Schurr . Erwin . Wallis . Robert S . Churchyard . Gavin . Mayanja-Kizza . Harriet . Boom . W Henry . 2018-09-01 . Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection . Nature Reviews Immunology . 18 . 9 . 575–589 . 10.1038/s41577-018-0025-3 . 1474-1741 . 6278832 . 29895826.
  26. Lu . L. L. . Smith . M. T. . Yu . K. K. Q. . Luedemann . C. . Suscovich . T. J. . Grace . P. S. . Cain . A. . Yu . W. H. . McKitrick . T. R. . Lauffenburger . D. . Cummings . R. D. . 2019 . IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure. . Nature Medicine . 25 . 6 . 977–987 . 10.1038/s41591-019-0441-3 . 1078-8956 . 31110348. 6559862 .
  27. Stein . Catherine M. . Zalwango . Sarah . Malone . LaShaunda L. . Won . Sungho . Mayanja-Kizza . Harriet . Mugerwa . Roy D. . Leontiev . Dmitry V. . Thompson . Cheryl L. . Cartier . Kevin C. . Elston . Robert C. . Iyengar . Sudha K. . 2008-12-31 . Genome Scan of M. tuberculosis Infection and Disease in Ugandans . PLOS ONE . en . 3 . 12 . e4094 . 10.1371/journal.pone.0004094 . 1932-6203 . 2605555 . 19116662. 2008PLoSO...3.4094S . free .
  28. Nakanjako . Damalie . Kamya . Moses . Daniel . Kyabayinze . Mayanja-Kizza . Harriet . Freers . Jurgen . Whalen . Christopher . Katabira . Elly . 2007-09-01 . Acceptance of Routine Testing for HIV among Adult Patients at the Medical Emergency Unit at a National Referral Hospital in Kampala, Uganda . AIDS and Behavior . en . 11 . 5 . 753–758 . 10.1007/s10461-006-9180-9 . 17096199 . 30398339 . 1573-3254.
  29. Chegou . Novel N. . Sutherland . Jayne S. . Malherbe . Stephanus . Crampin . Amelia C. . Corstjens . Paul L. A. M. . Geluk . Annemieke . Mayanja-Kizza . Harriet . Loxton . Andre G. . Spuy . Gian van der . Stanley . Kim . Kotzé . Leigh A. . 2016-09-01 . Diagnostic performance of a seven-marker serum protein biosignature for the diagnosis of active TB disease in African primary healthcare clinic attendees with signs and symptoms suggestive of TB . Thorax . en . 71 . 9 . 785–794 . 10.1136/thoraxjnl-2015-207999 . 0040-6376 . 27146200. 5486603 . free .
  30. Jacob . Shevin T. . Banura . Patrick . Baeten . Jared M. . Moore . Christopher C. . Meya . David . Nakiyingi . Lydia . Burke . Rebecca . Horton . Cheryl Lynn . Iga . Boaz . Wald . Anna . Reynolds . Steven J. . 2012 . The impact of early monitored management on survival in hospitalized adult Ugandan patients with severe sepsis: A prospective intervention study* . Critical Care Medicine . en-US . 40 . 7 . 2050–2058 . 10.1097/CCM.0b013e31824e65d7 . 22564958 . 3378757 . 0090-3493.
  31. Nakanjako . Damalie . Ssewanyana . Isaac . Mayanja-Kizza . Harriet . Kiragga . Agnes . Colebunders . Robert . Manabe . Yukari C. . Nabatanzi . Rose . Kamya . Moses R. . Cao . Huyen . 2011-02-08 . High T-cell immune activation and immune exhaustion among individuals with suboptimal CD4 recovery after 4 years of antiretroviral therapy in an African cohort . BMC Infectious Diseases . 11 . 1 . 43 . 10.1186/1471-2334-11-43 . 1471-2334 . 3065409 . 21299909 . free .
  32. Sullivan . Richard T. . Kim . Charles C. . Fontana . Mary F. . Feeney . Margaret E. . Jagannathan . Prasanna . Boyle . Michelle J. . Drakeley . Chris J. . Ssewanyana . Isaac . Nankya . Felistas . Mayanja-Kizza . Harriet . Dorsey . Grant . 2015-05-19 . FCRL5 Delineates Functionally Impaired Memory B Cells Associated with Plasmodium falciparum Exposure . PLOS Pathogens . en . 11 . 5 . e1004894 . 10.1371/journal.ppat.1004894 . 1553-7374 . 4438005 . 25993340 . free .
  33. Leidl . L. . Mayanja-Kizza . H. . Sotgiu . G. . Baseke . J. . Ernst . M. . Hirsch . C. . Goletti . D. . Toossi . Z. . Lange . C. . 2010-03-01 . Relationship of immunodiagnostic assays for tuberculosis and numbers of circulating CD4+ T-cells in HIV infection . European Respiratory Journal . en . 35 . 3 . 619–626 . 10.1183/09031936.00045509 . 0903-1936 . 19608590. 8348467 . free .

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