Hardcastle syndrome explained

Hardcastle syndrome
Synonyms:	Bone dysplasia-medullary fibrosarcoma syndrome,diaphyseal medullary stenosis-malignant fibrous histiocytoma syndrome

Hardcastle syndrome is a rare genetic disorder on chromosome 9 at 9p22-p21. It affects the long bones.^{[1] [2]} There is a high risk for histiocytoma.^[3]

References

1. Norton. K. I.. Wagreich. J. M.. Granowetter. L.. Martignetti. J. A.. September 1996. Diaphyseal medullary stenosis (sclerosis) with bone malignancy (malignant fibrous histiocytoma): Hardcastle syndrome. Pediatric Radiology. 26. 9. 675–677. 0301-0449. 8781110. 10.1007/BF01356833. 9795563.
2. Jamil. Wiqqas. Allami. Mohammad K.. Mbakada. Nikita. Kluge. Wolfram. December 2009. Total knee arthroplasty in a patient with Hardcastle syndrome. Orthopedics. 32. 12. 916. 10.3928/01477447-20091020-20. 1938-2367. 19968223.
3. Web site: Hardcastle syndrome. TheFreeDictionary.com. 2019-06-05.