Q-L53 is a subclade of haplogroup Q-M346. Q-L53 is defined by the presence of the L53 Single Nucleotide Polymorphism (SNP).
Q-L53 has descendants across much of Eurasia and in the pre-Columbian Americas. It is the parent of the major Haplogroup Q-L54 branch.
Q-L53 is currently defined by the L53 SNP as well as the L55, L213, L331, L475, and L476 SNPs.
This is Thomas Krahn at the Genomic Research Center's Draft tree Proposed Tree for haplogroup Q-L53. It shows the first two branch points.