Hans Chiari Explained

Hans Chiari
Birth Date:	4 September 1851
Birth Place:	Vienna, Austrian Empire
Death Place:	Strasbourg, German Empire
Nationality:	Austrian
Field:	Pathology
Known For:	Arnold–Chiari malformation Budd–Chiari syndrome Chiari network
Father:	Johann Baptist Chiari
Relatives:	Ottokar Chiari (brother)

Hans Chiari (^[1] pronounced as /de-AT/; 4 September 1851 − 6 May 1916) was a pathologist from Vienna, Austria-Hungary. He was the son of gynecologist Johann Baptist Chiari (1817–1854) and the brother of rhinolaryngologist Ottokar Chiari (1853–1918).

Biography

Chiari studied medicine in Vienna, where he was an assistant to Karl Freiherr von Rokitansky (1804–1878) and Richard Ladislaus Heschl (1824–1881). In 1878 he received his habilitation in pathological anatomy, and within a few years became an associate professor at the University of Prague. At Prague he was also superintendent of the pathological-anatomical museum. In 1906 he relocated to the University of Strasbourg as a professor of pathological anatomy.

Chiari's research dealt largely with postmortem examinations, and most of his numerous writings are the result of autopsies. In the 1890s he described a condition involving deformities of the cerebellum, and brainstem in children with herniation of the spinal cord.^[2] The phenomenon was later to become known as the "Arnold–Chiari malformation", named after Chiari and German pathologist, Julius Arnold (1835–1915). The malformation was given its name in 1907 by two of Dr. Arnold's students.^[3]

Another medical term named after Chiari is the Budd–Chiari syndrome, which is ascites and cirrhosis of the liver caused by an obstruction of the hepatic veins due to a blood clot. It is named in conjunction with British physician George Budd (1808–1882).^[4] Lastly, Chiari is also famous for describing the "Chiari network", an embryonic remnant found in the right atrium, first published in 1897.^[5]

Publications

• "Über Veränderungen des Kleinhirns infolge von Hydrocephalie des Grosshirns", Deutsche medicinische Wochenschrift, Berlin, 1891, 17: 1172–1175 – On cerebellar changes caused by hydrocephalus of the cerebrum.
• "Über Veränderungen des Kleinhirns, der Pons und der Medulla oblongata, infolge von congenitaler Hydrocephalie des Grosshirns", Denkschriften der Akademie der Wissenschaften in Wien, 1895, 63: 71. – On changes to the cerebellum, pons and the medulla oblongata, caused by hydrocephalus of the cerebrum.^[2]

See also

• Pathology
• List of pathologists

References

• Loukas. Marios. Noordeh Nima . Shoja Mohammadali M . Pugh Jeffrey . Oakes W Jerry . Tubbs R Shane . March 2008. Hans Chiari (1851–1916). Child's Nervous System. 24. 3. 407–9. 18066558. 10.1007/s00381-007-0535-y . 28160855.
• Arnett. Bridgette. June 2003. Arnold–Chiari malformation. Arch. Neurol.. 60. 6. 898–900. 12810499. 10.1001/archneur.60.6.898 .
• Pearce. J.M.S.. January 2000. Arnold Chiari, or "Cruveilhier Cleland Chiari" malformation. J. Neurol. Neurosurg. Psychiatry. 68. 1. 13. 10601393. 10.1136/jnnp.68.1.13. 1760604 .
• Koehler. P J. November 1991. Chiari's description of cerebellar ectopy (1891). With a summary of Cleland's and Arnold's contributions and some early observations on neural-tube defects. J. Neurosurg.. 75. 5. 823–6. 1919713. 10.3171/jns.1991.75.5.0823 .
• Lagerkvist. B. Olsen L. August 1991. [The men behind the syndrome. John Cleland, Hans Chiari and Julius Arnold—3 men behind a new phenomenon. Brain stem defects in children with myelocele]. Läkartidningen. 88. 32–33. 2610–1. 1881219 .
• Chiari. H. 1987. Concerning alterations in the cerebellum resulting from cerebral hydrocephalus. 1891. Pediatric Neuroscience. 13. 1. 3–8. 3317333. 10.1159/000120293 .
• Wilkins. R H. Brady I A. October 1971. The Arnold–Chiari malformations. Arch. Neurol.. 25. 4. 376–9. 10.1001/archneur.1971.00490040102013. 4938787 .

External links

• Weill Cornell Chiari CARE http://weillcornellbrainandspine.org/chiari
• The Chiari Institute https://web.archive.org/web/20080505070336/http://chiariinstitute.com/
• The Chiari Center of Wisconsin http://www.wichiaricenter.org/
• Hans Chiari @ Who Named It

Notes and References

1. Web site: Chiari malformation. Cambridge Dictionary. Cambridge University Press.
2. http://www.whonamedit.com/synd.cfm/1154.html Arnold–Chiari malformation
3. http://www.whonamedit.com/doctor.cfm/280.html Julius Arnold
4. http://www.whonamedit.com/synd.cfm/1335.html Budd-Chiari syndrome
5. 3248639 . 21909773 . 10.1007/s00246-011-0114-6 . 33 . 1 . Chiari's network as a cause of fetal and neonatal pathology . Pediatr Cardiol . 188–91 . Bendadi . F . van Tijn . DA . Pistorius . L . Freund . MW. 2012 .