| Hamza Mirza | |||||
| Succession: | Safavid Crown Prince | ||||
| Reign: | 11 February 1578-24/26 November 1586 | ||||
| Reign-Type: | Tenure | ||||
| Regent: | Mohammad Khodabanda | ||||
| Reg-Type: | Shah | ||||
| Successor: | Abbas the Great | ||||
| Birth Date: | 4 September 1568 | ||||
| Birth Place: | Herat, Iran | ||||
| Death Date: | 24/26 November 1586 (aged 19) | ||||
| Death Place: | Isfahan, Iran | ||||
| Burial Place: | Karbala | ||||
| Dynasty: | Safavid | ||||
| Father: | Mohammad Khodabanda | ||||
| Mother: | Khayr al-Nisa Begum | ||||
| Issue: | Ismail Mirza Haydar Mirza | ||||
| Religion: | Twelver Shia Islam | ||||
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Hamza Mirza (Persian: حمزه میرزا|Ḥamza Mīrzā; 4 September 1568 – 24/26 November 1586) was the Safavid crown prince of Iran during the reign of his father Mohammad Khodabanda . His mother was Khayr al-Nisa Begum, a Mar'ashi princess from Mazandaran.