| Hamilton-Wenham Regional High School | |
| Motto: | "A Passion For Learning" |
| Type: | Public secondary school |
| Streetaddress: | 775 Bay Road |
| City: | South Hamilton |
| State: | Massachusetts |
| Country: | United States |
| Zipcode: | 01982 |
| Coordinates: | 42.6286°N -70.8481°W |
| Founded: | 1962 |
| Grades: | 9-12 |
| Enrollment: | 563 (2018-19)[1] |
| Teaching Staff: | 47.70 |
| Ratio: | 11.74 |
| Principal: | Bryan Menegoni |
| Superintendent: | Eric Tracy [2] |
| District: | Hamilton-Wenham Regional School District |
| Nickname: | Generals |
| Colors: | Navy Blue and White |
| Conference: | Cape Ann League (CAL) |
Hamilton-Wenham Regional High School (HWRHS) is a public high school in South Hamilton, Massachusetts, United States. It is the only high school in the Hamilton-Wenham Regional School District, which has its administrative offices in Wenham, Massachusetts. The high school serves the towns of Hamilton, and Wenham.