HTR3E explained

5-hydroxytryptamine receptor 3E is a protein that in humans is encoded by the HTR3E gene.^{[1] [2]} The protein encoded by this gene is a subunit of the 5-HT3 receptor.

Further reading

• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2002 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Karnovsky AM, Gotow LF, McKinley DD, etal . A cluster of novel serotonin receptor 3-like genes on human chromosome 3 . Gene . 319 . 137–48 . 2003 . 14597179 . 10.1016/S0378-1119(03)00803-5 .
• Nalivaiko E, Sgoifo A . Central 5-HT receptors in cardiovascular control during stress . Neuroscience and Biobehavioral Reviews . 33 . 2 . 95–106 . 2009 . 18573276 . 10.1016/j.neubiorev.2008.05.026 . 44767978 .
• Kapeller J, Houghton LA, Mönnikes H, etal . First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor-type 3E gene with diarrhea predominant irritable bowel syndrome . Hum. Mol. Genet. . 17 . 19 . 2967–77 . 2008 . 18614545 . 10.1093/hmg/ddn195 . free .

Notes and References

1. Niesler B, Frank B, Kapeller J, Rappold GA . Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E . Gene . 310 . 101–11 . Jun 2003 . 12801637 . 10.1016/S0378-1119(03)00503-1 .
2. Peters JA, Kelley SP, Dunlop JI, Kirkness EF, Hales TG, Lambert JJ . The 5-hydroxytryptamine type 3 (5-HT3) receptor reveals a novel determinant of single-channel conductance . Biochem Soc Trans . 32 . Pt3 . 547–52 . May 2004 . 15157181 . 10.1042/BST0320547 .