HSPA6 explained

Heat shock 70 kDa protein 6 is a protein that in humans is encoded by the HSPA6 gene.^{[1] [2]}

Further reading

• Leung TK, Rajendran MY, Monfries C, etal . The human heat-shock protein family. Expression of a novel heat-inducible HSP70 (HSP70B') and isolation of its cDNA and genomic DNA. . Biochem. J. . 267 . 1 . 125–32 . 1990 . 2327978 . 10.1042/bj2670125. 1131254 .
• Schiller P, Amin J, Ananthan J, etal . Cis-acting elements involved in the regulated expression of a human HSP70 gene. . J. Mol. Biol. . 203 . 1 . 97–105 . 1988 . 3184191 . 10.1016/0022-2836(88)90094-0 .
• Rensing SA, Maier UG . Phylogenetic analysis of the stress-70 protein family. . J. Mol. Evol. . 39 . 1 . 80–6 . 1994 . 7545947 . 10.1007/BF00178252 . 1994JMolE..39...80R . 37505045 .
• Furlini G, Vignoli M, Re MC, etal . Human immunodeficiency virus type 1 interaction with the membrane of CD4+ cells induces the synthesis and nuclear translocation of 70K heat shock protein. . J. Gen. Virol. . 75 . 1. 193–9 . 1994 . 7906708 . 10.1099/0022-1317-75-1-193 . free .
• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. . Gene . 138 . 1–2 . 171–4 . 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. . Gene . 200 . 1–2 . 149–56 . 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 .
• Mercier PA, Winegarden NA, Westwood JT . Human heat shock factor 1 is predominantly a nuclear protein before and after heat stress. . 112 . J. Cell Sci. . (Pt 16) . 2765–74 . 1999 . 16 . 10.1242/jcs.112.16.2765 . 10413683 .
• O'Keeffe B, Fong Y, Chen D, etal . Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription. . J. Biol. Chem. . 275 . 1 . 279–87 . 2000 . 10617616 . 10.1074/jbc.275.1.279 . free .
• Agostini I, Popov S, Li J, etal . Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex. . Exp. Cell Res. . 259 . 2 . 398–403 . 2000 . 10964507 . 10.1006/excr.2000.4992 .
• Gurer C, Cimarelli A, Luban J . Specific incorporation of heat shock protein 70 family members into primate lentiviral virions. . J. Virol. . 76 . 9 . 4666–70 . 2002 . 11932435 . 10.1128/JVI.76.9.4666-4670.2002 . 155079 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Lim MC, Brooke SM, Sapolsky RM . gp120 neurotoxicity fails to induce heat shock defenses, while the over expression of hsp70 protects against gp120. . Brain Res. Bull. . 61 . 2 . 183–8 . 2003 . 12832005 . 10.1016/S0361-9230(03)00113-8 . 35451084 .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .

Notes and References

1. Leung TK, Hall C, Rajendran M, Spurr NK, Lim L . The human heat-shock genes HSPA6 and HSPA7 are both expressed and localize to chromosome 1 . Genomics . 12 . 1 . 74–9 . Mar 1992 . 1346391 . 10.1016/0888-7543(92)90409-L .
2. Web site: Entrez Gene: HSPA6 heat shock 70kDa protein 6 (HSP70B').