St. Kitts joined the 5th Destroyer Flotilla of the Home Fleet upon commission. In 1948, St. Kitts deployed to the Arctic to join the aircraft carrier, along with a variety of other ships, including other Battle-class destroyers during experiments in that region. In 1953, St. Kitts took part in the large Fleet Review at Spithead to celebration the Coronation of Queen Elizabeth II. St. Kitts was positioned in the middle of her sister ships and .[1] St. Kitts was subsequently placed in Reserve.
In 1954, St. Kitts joined the 3rd Destroyer Flotilla, also part of the Home Fleet. In 1955, St. Kitts, still with the 3rd Flotilla, deployed to the Mediterranean, and took part in the Suez Crisis, which had occurred after the nationalisation of the Suez Canal by the Egyptian leader Nasser. During Operation Musketeer, the invasion of Egypt, St. Kitts performed a variety of duties, including escorting the carrier, as well as participating in the naval bombardment of Port Said. That same year, St. Kitts, along with the rest of the Flotilla, left the Mediterranean to join the Home Fleet.
In 1957, St. Kitts was decommissioned, being scrapped in 1962 at Sunderland.