She took part in Admiral Richard Howe's notable action against the French fleet under the Comte d'Estaing on 11 August 1778. Two days subsequent to this, she attacked the 90-gun Languedoc, which had been dismasted the day before in a storm, and raked her.
She returned to England in November 1780 and underwent a refit and replacement of her coppering until February 1781, before recommissioning under Captain John Henry and returning to the North American station. The Renown took part in Kempenfelt's Action on 12 December 1781. She finally returned home and paid off out of commission in August 1784. She was fitted as a lazarette at Chatham Dockyard in March 1794, but was eventually broken up at Sheerness in December 1794.