HLA-B35 explained

B*3508-β2MG with bound peptide

major histocompatibility complex (human), class I, B35

AllelesB*3501, 3502, 3503, . . .
Structure (See HLA-B)
Symbol(s)HLA-B ,
EBI-HLAB*3501 ,,
EBI-HLAB*3502
EBI-HLAB*3503
EBI-HLAB*3504
EBI-HLAB*3505
EBI-HLAB*3506
EBI-HLAB*3507
EBI-HLAB*3508 ,
EBI-HLAB*3509
EBI-HLAB*3510
EBI-HLAB*3511
EBI-HLAB*3512
Locuschr.6 6p21.31

HLA-B35 (B35) is an HLA-B serotype. The serotype identifies the more common HLA-B*35 gene products.[1] B35 is one of the largest B serotype groups, it currently has 97 known nucleotide variants and 86 polypeptide isoforms. (For terminology help see: HLA-serotype tutorial). This variant is particularly susceptible to HIV infection.

Serotype

B35 serotype recognition of Some HLA B*35 allele-group gene products[2]
B*35 B35Sample
allele % % size (N)
3501 98 2023
3502 72 1013
3503 94 1226
3504 100 26
3505 94 231
3506 79 10
3508 91 349
3509 68 3
3510 75 12
3511 67 17
3512 78 422
3514 79 29
3520 42 23

Notes and References

  1. 2848993 . 2010 . Marsh . S. G. . Nomenclature for factors of the HLA system, 2010 . Tissue Antigens . 75 . 4 . 291–455 . Albert . E. D. . Bodmer . W. F. . Bontrop . R. E. . Dupont . B. . Erlich . H. A. . Fernández-Viña . M. . Geraghty . D. E. . Holdsworth . R. . Hurley . C. K. . Lau . M. . Lee . K. W. . Mach . B. . Maiers . M. . Mayr . W. R. . Müller . C. R. . Parham . P. . Petersdorf . E. W. . Sasazuki . T. . Strominger . J. L. . Svejgaard . A. . Terasaki . P. I. . Tiercy . J. M. . Trowsdale . J. . 20356336 . 10.1111/j.1399-0039.2010.01466.x .
  2. http://www.ebi.ac.uk/imgt/hla/allele.html derived from IMGT/HLA