HLA-A9 explained
HLA-A9 (A9) is a broad antigen
HLA-
A serotype that recognized the
HLA-A23 and
HLA-A24 serotypes.
[1] A*2402 appears to have evolved from A*23 alleles by a process of gene conversion. The A23 is more common in Africa and regions proximal to Africa. A24 is at very high frequencies in Austronesia and certain indigenous peoples of the Arctic,
[2] [3] [4] North America,
[5] South America
[6] and West Pacific Rim. While it is common over most of Eurasia, it is found at low abundance in NW Europe. A24 appears to have been carried by the first colonizers of South Eastern Asia.
Subpages for A9 serotypes | - | Split antigen serotypes
of A9 | - | | - | | - | |
Notes and References
- Fussell H, Thomas M, Street J, Darke C . HLA-A9 antibodies and epitopes . Tissue Antigens . 47 . 4 . 307–12 . 1996 . 8773320 . 10.1111/j.1399-0039.1996.tb02558.x .
- Lou H, Li HC, Kuwayama M, etal . HLA class I and class II of the Nivkhi, an indigenous population carrying HTLV-I in Sakhalin, Far Eastern Russia . Tissue Antigens . 52 . 5 . 444–51 . 1998 . 9864034 . 10.1111/j.1399-0039.1998.tb03071.x .
- Nelson JL, Boyer G, Templin D, etal . HLA antigens in Tlingit Indians with rheumatoid arthritis . Tissue Antigens . 40 . 2 . 57–63 . 1992 . 1412417 . 10.1111/j.1399-0039.1992.tb01960.x .
- Welinder L, Graugaard B, Madsen M . HLA antigen and gene frequencies in Eskimos of East Greenland . Eur. J. Immunogenet. . 27 . 2 . 93–7 . 2000 . 10792425 . 10.1046/j.1365-2370.2000.00209.x .
- Leffell MS, Fallin MD, Hildebrand WH, Cavett JW, Iglehart BA, Zachary AA . HLA alleles and haplotypes among the Lakota Sioux: report of the ASHI minority workshops, part III . Hum. Immunol. . 65 . 1 . 78–89 . 2004 . 14700599 . 10.1016/j.humimm.2003.10.001 .
- Fleischhauer K, Agostino A, Zino E, etal . Molecular characterization of HLA class I in Colombians carrying HLA-A2: high allelic diversity and frequency of heterozygotes at the HLA-B locus . Tissue Antigens . 53 . 6 . 519–26 . 1999 . 10395101 . 10.1034/j.1399-0039.1999.530601.x .
