HLA-A31 explained

There is substantive false reaction of A30 with A*3101, otherwise serological identification is good.

Haplotypes

HLA A31 haplotype frequencies
freq
ref. Population (%)
Colspan = 3 A31-B35
(A*310102:Cw*0401:B*3501)
Lakota Sioux (USA) 4.1
Indig American (USA) 3.7
Mestizo (Guad. Mexico) 1.5[1]
Tibetan 1.1
Jews (England) 1.3
Tibetan 1.1
Italian 0.6
Japanese 0.5
French 0.5
Choushan (China) 0.4
German 0.3
Colspan = 3 A31-B39
(A*310102:Cw*0701:B*3901)
Mixtec (Oax. Mexico) 10.0
Lakota Sioux (USA) 1.6
Japanese 0.3
German 0.1
Colspan = 3 A31-B48
(A*310102:B*4801)
Orochon (Russia) 6.0
Maya (Guatemala) 3.5
Buriat 3.4
Japanese 0.3
Colspan = 3 A31-B51
(A*310102:B*5101)
Ainu (Hokkaido Japan) 8.9
Indig. Brazil 5.8
Orochon (Russia) 5.3
Indig American (USA) 4.3
Tibetan 3.3
Inner Mongolian 3.0
Japanese 3.0
Portuguese 1.6
Korean 1.2
Italian 0.9
French 0.5
German 0.3
Choushan (China) 0.2
Colspan = 3 (A*310102:B*5102)
Tarahumura (Mexico) 5.7
Vietnamese 1.0
Colspan = 3 A31-B60
(A*310102:Cw*0304:B*4001)
Lusaka (Zambia) 2.3
Yakuts (Russia) 2.0
Irish 0.7
Choushan (China) 0.7
Japan 0.6
Dutch 0.6
German 0.4
Colspan = 3 A31-B62
(A*310102:B*1501)
Nivkhi (Sakalin, Russia)12.5
Yakut(Russia)5.5
Indig. Brazil4.1
Manchu1.1
Japan0.4
German0.2
Choushan (China) 0.2

Examination of A31 haplotypes reveals a probable connection across northern Eurasia during the prehistoric period. Frequencies of the more 'tale-tell' haplotypes (A31-B60, B61, and B62) fall from NE to SW Europe. Other haplotypes appears to have spread from the Middle East (A31-B51 and A31-B35).

Notes and References

  1. B*3512