HIPK3 explained

Homeodomain-interacting protein kinase 3 is an enzyme that in humans is encoded by the HIPK3 gene.^{[1] [2] [3]}

Further reading

• Moilanen AM . Activation of Androgen Receptor Function by a Novel Nuclear Protein Kinase . Mol. Biol. Cell . 9 . 9 . 2527–43 . 1999 . 9725910 . 10.1091/mbc.9.9.2527. 25523 . vanc. Karvonen U . Poukka H . 3 . Jänne . OA . Palvimo . JJ .
• Scaffidi C . Phosphorylation of FADD/ MORT1 at serine 194 and association with a 70-kDa cell cycle-regulated protein kinase . J. Immunol. . 164 . 3 . 1236–42 . 2000 . 10640736 . 10.4049/jimmunol.164.3.1236. vanc. Volkland J . Blomberg I . 3 . Hoffmann . I . Krammer . PH . Peter . ME . free.
• Nupponen NN, Visakorpi T . Assignment of the protein kinase homolog of YAK1 (HIPK3) to human chromosome band 11p13 by in situ hybridization . Cytogenet. Cell Genet. . 87 . 1–2 . 102–3 . 2000 . 10640824 . 10.1159/000015404 . 5798220 .
• Dias Neto E . Shotgun sequencing of the human transcriptome with ORF expressed sequence tags . Proc. Natl. Acad. Sci. U.S.A. . 97 . 7 . 3491–6 . 2000 . 10737800 . 10.1073/pnas.97.7.3491 . 16267 . vanc. Correa RG . Verjovski-Almeida S . 3 . Briones . MR . Nagai . MA . Da Silva Jr . W . Zago . MA . Bordin . S . Costa . FF . 2000PNAS...97.3491D . free .
• Minty A, Dumont X, Kaghad M, Caput D . Covalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motif . J. Biol. Chem. . 275 . 46 . 36316–23 . 2000 . 10961991 . 10.1074/jbc.M004293200 . free .
• Rochat-Steiner V . Fist/Hipk3: A FAS/Fadd-Interacting Serine/Threonine Kinase That Induces Fadd Phosphorylation and Inhibits FAS-Mediated Jun Nh2-Terminal Kinase Activation . J. Exp. Med. . 192 . 8 . 1165–74 . 2000 . 11034606 . 10.1084/jem.192.8.1165 . 2311455 . vanc. Becker K . Micheau O . 3 . Schneider . P. . Burns . K. . Tschopp . J. .
• Curtin JF, Cotter TG . JNK regulates HIPK3 expression and promotes resistance to Fas-mediated apoptosis in DU 145 prostate carcinoma cells . J. Biol. Chem. . 279 . 17 . 17090–100 . 2004 . 14766760 . 10.1074/jbc.M307629200 . free .
• Colland F . Functional Proteomics Mapping of a Human Signaling Pathway . Genome Res. . 14 . 7 . 1324–32 . 2004 . 15231748 . 10.1101/gr.2334104 . 442148 . vanc. Jacq X . Trouplin V . 3 . Mougin . C . Groizeleau . C . Hamburger . A . Meil . A . Wojcik . J . Legrain . P .
• Rush J . Immunoaffinity profiling of tyrosine phosphorylation in cancer cells . Nat. Biotechnol. . 23 . 1 . 94–101 . 2005 . 15592455 . 10.1038/nbt1046 . vanc. Moritz A . Lee KA . 3 . Guo . Ailan . Goss . Valerie L . Spek . Erik J . Zhang . Hui . Zha . Xiang-Ming . Polakiewicz . Roberto D . 7200157 .
• Venables JP . Up-regulation of the ubiquitous alternative splicing factor Tra2beta causes inclusion of a germ cell-specific exon . Hum. Mol. Genet. . 14 . 16 . 2289–303 . 2005 . 16000324 . 10.1093/hmg/ddi233 . vanc. Bourgeois CF . Dalgliesh C . 3 . Kister . L . Stevenin . J . Elliott . DJ .
• Taylor TD . Human chromosome 11 DNA sequence and analysis including novel gene identification . Nature . 440 . 7083 . 497–500 . 2006 . 16554811 . 10.1038/nature04632 . vanc. Noguchi H . Totoki Y . 3 . Toyoda . Atsushi . Kuroki . Yoko . Dewar . Ken . Lloyd . Christine . Itoh . Takehiko . Takeda . Tadayuki . 2006Natur.440..497T . free .
• Lan HC . Cyclic AMP Stimulates SF-1-Dependent CYP11A1 Expression through Homeodomain-Interacting Protein Kinase 3-Mediated Jun N-Terminal Kinase and c-Jun Phosphorylation . Mol. Cell. Biol. . 27 . 6 . 2027–36 . 2007 . 17210646 . 10.1128/MCB.02253-06 . 1820514 . vanc. Li HJ . Lin G . 3 . Lai . P.-Y. . Chung . B.-c. .

Notes and References

1. Begley DA, Berkenpas MB, Sampson KE, Abraham I . Identification and sequence of human PKY, a putative kinase with increased expression in multidrug-resistant cells, with homology to yeast protein kinase Yak1 . Gene . 200 . 1–2 . 35–43 . Dec 1997 . 9373137 . 10.1016/S0378-1119(97)00350-8 .
2. Kim YH, Choi CY, Lee SJ, Conti MA, Kim Y . Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors . J Biol Chem . 273 . 40 . 25875–9 . Nov 1998 . 9748262 . 10.1074/jbc.273.40.25875 . free .
3. Web site: Entrez Gene: HIPK3 homeodomain interacting protein kinase 3.