HIE-124 explained

Drug Name:HIE-124
Pubchem:11447815
Chemspiderid:9622668
Unii:JS6A6EQZ44
Chembl:450014
Iupac Name:Ethyl 8-oxo-6,7-dihydro-5H-[1,3]thiazolo[3,2-a][1,3]diazepine-3-carboxylate
C:10
H:12
N:2
O:3
S:1
Smiles:O=C(C1=CSC(N1CCC2)=NC2=O)OCC
Stdinchi:1S/C10H12N2O3S/c1-2-15-9(14)7-6-16-10-11-8(13)4-3-5-12(7)10/h6H,2-5H2,1H3
Stdinchikey:UXGPDPNGDCOQBY-UHFFFAOYSA-N

HIE-124 is an investigational nonbenzodiazepine drug being researched for its short acting hypnotic effects.[1]

Notes and References

  1. Kadi A, El-Kashef H, Abdel-Aziz A, Hassan G, Tettey J, Grant M, Lehmann J, El-Subbagh H . Synthesis, ultra-short acting hypnotic activity, and metabolic profile of ethyl 8-oxo-5,6,7,8-tetrahydro-thiazolo[3,2-a] [1,3]diazepin-3-carboxylate (HIE-124) . Archiv der Pharmazie . 341 . 2 . 81–89 . February 2008 . 18214840 . 10.1002/ardp.200700132 . 12263886 .