HEXIM2 explained

Protein HEXIM2 is a protein that in humans is encoded by the HEXIM2 gene.^{[1] [2]}

Further reading

• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Beausoleil SA, Jedrychowski M, Schwartz D, etal . Large-scale characterization of HeLa cell nuclear phosphoproteins. . Proc. Natl. Acad. Sci. U.S.A. . 101 . 33 . 12130–5 . 2004 . 15302935 . 10.1073/pnas.0404720101 . 514446 . 2004PNAS..10112130B . free .
• Petroziello J, Yamane A, Westendorf L, etal . Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer. . Oncogene . 23 . 46 . 7734–45 . 2004 . 15334068 . 10.1038/sj.onc.1207921 . free .
• Yik JH, Chen R, Pezda AC, Zhou Q . Compensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcription. . J. Biol. Chem. . 280 . 16 . 16368–76 . 2005 . 15713661 . 10.1074/jbc.M500912200 . free .
• Byers SA, Price JP, Cooper JJ, etal . HEXIM2, a HEXIM1-related protein, regulates positive transcription elongation factor b through association with 7SK. . J. Biol. Chem. . 280 . 16 . 16360–7 . 2005 . 15713662 . 10.1074/jbc.M500424200 . free .
• Li Q, Price JP, Byers SA, etal . Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated at threonine 186. . J. Biol. Chem. . 280 . 31 . 28819–26 . 2005 . 15965233 . 10.1074/jbc.M502712200 . free .
• Fraldi A, Varrone F, Napolitano G, etal . Inhibition of Tat activity by the HEXIM1 protein. . Retrovirology . 2 . 1. 42 . 2006 . 15992410 . 10.1186/1742-4690-2-42 . 1183248 . free .

Notes and References

1. Michels AA, Nguyen VT, Fraldi A, Labas V, Edwards M, Bonnet F, Lania L, Bensaude O . MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner . Mol Cell Biol . 23 . 14 . 4859–69 . Jun 2003 . 12832472 . 162212 . 10.1128/MCB.23.14.4859-4869.2003 .
2. Web site: Entrez Gene: HEXIM2 hexamthylene bis-acetamide inducible 2.