HIST1H2BJ explained

Histone H2B type 1-J is a protein that in humans is encoded by the HIST1H2BJ gene.^{[1] [2] [3]}

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33.

Further reading

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Notes and References

1. Zhong R, Roeder RG, Heintz N . The primary structure and expression of four cloned human histone genes . Nucleic Acids Res . 11 . 21 . 7409–7425 . Jan 1984 . 6647026 . 326492 . 10.1093/nar/11.21.7409 .
2. Marzluff WF, Gongidi P, Woods KR, Jin J, Maltais LJ . The human and mouse replication-dependent histone genes . Genomics . 80 . 5 . 487–498 . Oct 2002 . 12408966 . 10.1016/S0888-7543(02)96850-3 .
3. Web site: Entrez Gene: HIST1H2BJ histone cluster 1, H2bj.