Gymnochthebius seminole is a species of tiny beetle in the family Hydraenidae. It is known only from a single adult male specimen collected in a "sawgrass-mangrove area" along the Snake Bight Trail north of Flamingo in Everglades National Park, Florida on 27 August 1965. This specimen was 1.2mm long, with a relatively robust body. It is most similar to G. oppositus. The species is named for the Seminole people of Florida.