Guy Dodson Explained

Guy Dodson
Birth Name:George Guy Dodson
Birth Date:1937 1, df=yes
Birth Place:Palmerston North, New Zealand
Death Place:York, England
Fields:X-ray crystallography
Alma Mater:University of New Zealand (BSc, PhD)
Spouse:Eleanor Dodson
Children:4

George Guy Dodson FRS FMedSci (13 January 1937 – 24 December 2012), was a British biochemist who specialised in protein crystallography at the University of York.[1] [2] [3] [4] [5] [6]

Education

Dodson graduated from the University of New Zealand where he was awarded a Bachelor of Science and Doctor of Philosophy degrees. His doctoral thesis, completed in 1961, was titled An X-ray analysis of an alkaloid and some investigation into nickel bis-salicylaldahyde triethylene tetramine.[7]

Career

Dodson did postdoctoral research with Dorothy Hodgkin at the University of Oxford.[8] [9] [10] [11] He devised along with Hodgkin, very intricate experimental, crystallographic and computer techniques that led to the final solution of the structure of insulin. Dodson was head of the structural biology laboratories at the University of York and National Institute for Medical Research, London. During his career he collaborated with many scientists including Dale Wigley, Gideon Davies,[3] Andrzej Brzozowski,[12] Leo Brady[13] and Max Perutz.[14]

Awards and honours

Dodson was elected a Fellow of the Royal Society (FRS)[15] in 1994. His nomination reads

Dodson was also a Foreign Member of the Indian National Science Academy (ForMemINSA) and the Academy of Medical Sciences (FMedSci).

He was a recipient of the RSC Structural Chemistry Award in 1991.

Personal life

Dodson was married to the scientist Eleanor Dodson with whom he had four children.

Notes and References

  1. .
  2. 10.3389/fendo.2013.00033. In Memoriam: Guy Dodson (1937–2012). Frontiers in Endocrinology. 4. 2013. De Meyts . P. . 33. 3604789. free.
  3. Wigley . D.B. . Davies . G.J.. Gideon Davies . Dodson . E.J.. Eleanor Dodson . Maxwell . A . Dodson . G. Guy Dodson . 1991 . Crystal structure of an N-terminal fragment of the DNA gyrase B protein . Nature . 351 . 6328. 624–629 . 1646964 . 10.1038/351624a0 . 1991Natur.351..624W . 4373125 .
  4. 10.1038/365362a0. Structure and function of endoglucanase V. Nature. 365. 6444. 362–4. 1993. Davies . G. J. . Dodson . G. G. . Hubbard . R. E. . Tolley . S. P. . Dauter . Z. . Wilson . K. S. . Hjort . C. . Mikkelsen . J. M. L. . Rasmussen . G. . Schülein . M. . 8377830. 1993Natur.365..362D. 4277867.
  5. 10.1107/S0907444913004186. Guy Dodson FRS (1937–2012). Acta Crystallographica Section D. 69. 3. 490–492. 2013. Baker . E. N.. free.
  6. https://publications.parliament.uk/pa/cm201011/cmselect/cmsctech/writev/727/m16.htm Written evidence submitted by Professor Guy Dodson, FRS, FMS, ForMemINSA
  7. Dodson . George . 1961 . Doctoral thesis . An X-ray analysis of an alkaloid and some investigation into nickel bis-salicylaldahyde triethylene tetramine . ResearchSpace@Auckland, University of Auckland . 2292/56154.
  8. Blundell . T. L. . Tom Blundell. Dodson . G. G. . Guy Dodson. Dodson . E. . Eleanor Dodson. Hodgkin . D. C. . Dorothy Hodgkin. Vijayan . M. . X-ray analysis and the structure of insulin . Recent Progress in Hormone Research . 27 . 1–40 . 1971 . 10.1016/b978-0-12-571127-2.50025-0 . 4946130. 9780125711272 .
  9. Blundell . T.L. . Tom Blundell. Cutfield . J.F. . Cutfield . S.M. . Dodson . E.J. . Eleanor Dodson. Dodson . G.G. . Guy Dodson. Hodgkin . D.C. . Dorothy Hodgkin. Mercola . D.A. . Vijayan . M. . 10.1038/231506a0 . Atomic positions in rhombohedral 2-zinc insulin crystals . Nature . 231 . 5304 . 506–511 . 1971 . 4932997. 1971Natur.231..506B . 4158731 .
  10. Adam . M. G. . Coller . L. . Hodgkin . D. C.. Dorothy Hodgkin . Dodson . G. G. . Guy Dodson. X-ray crystallographic studies on zinc insulin crystals . The American Journal of Medicine . 40 . 5 . 667–671 . 1966 . 5941965 . 10.1016/0002-9343(66)90146-X.
  11. Dodson . Guy. Guy Dodson. 10.1098/rsbm.2002.0011 . Dorothy Mary Crowfoot Hodgkin, O.M. 12 May 1910 – 29 July 1994 . . 48 . 179–219 . 2002 . 13678070. 61764553.
  12. 10.1038/351491a0. A model for interfacial activation in lipases from the structure of a fungal lipase-inhibitor complex. Nature. 351. 6326. 491–494. 1991. Brzozowski . A. M.. Derewenda . U.. Derewenda . Z. S.. Dodson . G. G.. Lawson . D. M.. Turkenburg . J. P.. Bjorkling . F.. Huge-Jensen . B.. Patkar . S. A.. Thim . L. . 2046751. 1991Natur.351..491B. 4343187.
  13. 10.1038/343767a0. A serine protease triad forms the catalytic centre of a triacylglycerol lipase. Nature. 343. 6260. 767–70. 1990. Brady . L. . Brzozowski . A. M. . Derewenda . Z. S. . Dodson . E. . Dodson . G. . Tolley . S. . Turkenburg . J. P. . Christiansen . L. . Huge-Jensen . B. . Norskov . L. . Thim . L. . Menge . U. . 2304552. 1990Natur.343..767B . 4308111.
  14. 10.1146/annurev.biophys.27.1.1. The Stereochemical Mechanism of the Cooperative Effects in Hemoglobin Revisited. Annual Review of Biophysics and Biomolecular Structure. 27. 1–34. 1998. Perutz . M. F.. Wilkinson . A. J.. Paoli . M.. Dodson . G. G.. 9646860.
  15. Dodson. Eleanor. 2020. Guy Dodson. 13 January 1937—24 December 2012. Biographical Memoirs of Fellows of the Royal Society. 68 . 151–174 . 10.1098/rsbm.2019.0042 . 212737449 . free.

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