| Gurbuz District | |
| Native Name: | ګربز ولسوالۍ ولسوالی گربز |
| Pushpin Map: | Afghanistan |
| Pushpin Label Position: | above |
| Pushpin Mapsize: | 280px |
| Pushpin Map Caption: | Location in Afghanistan |
| Subdivision Type: | Country |
| Subdivision Name: |  Afghanistan |
| Subdivision Type1: | Province |
| Subdivision Name1: | Khost |
| Subdivision Type2: | Capital |
| Subdivision Name2: | Sekhamir Kalay |
| Government Type: | Central |
| Leader Title: | District Governor |
| Leader Name: | Abdulhai Zazi |
| Population As Of: | 2020 |
| Population Total: | 29,627 |
| Timezone: | Afghanistan Standard Time |
| Utc Offset: | +4:30 |
| Coordinates: | 33.2875°N 69.9125°W |
Gurbuz District (ps|ګربز ولسوالۍ, fa|ولسوالی گربز) is situated in the southeast part of Khost Province, Afghanistan. It borders Tani District to the west, Mando Zayi and Khost districts to the north and Khyber Pakhtunkhwa in Pakistan to the southeast. Governor of Gurbuz District is Abdulhai Zazi.[1] The Afghan National Security Forces (ANSF) are responsible for all law enforcement activities in the district.
According to Afghanistan's National Statistics and Information Authority (NSIA), the 2020 estimated population of the district was 29,627 people.[2] The district center is the village of Sekhamir Kalay situated in the northwestern part of the district. It is inhabited by Gurbuz, a Wazir subtribe.[3]