| Guo Youzhi | |
| Native Name: | 郭攸之 |
| Office: | Palace Attendant (侍中) |
| Office1: | Gentleman of the Yellow Gate (黃門侍郎) |
| Monarch1: | Liu Shan |
| Birth Date: | Unknown |
| Birth Place: | Nanyang, Henan |
| Death Date: | Unknown |
| Occupation: | Official |
| Blank1: | Courtesy name |
| Data1: | Yanchang (演長) |
Guo Youzhi (third century), courtesy name Yanchang, was an official of the state of Shu Han in the Three Kingdoms period (220–280) of China. Zhuge Liang, the Imperial Chancellor of Shu, described Guo Youzhi in the Chu Shi Biao as exceedingly loyal and faithful, and named him along with Dong Yun and Fei Yi as the more competent officials in Shu while advising the Shu emperor Liu Shan to make good use of their talents.