| Official Name: | Guisa |
| Settlement Type: | Municipality |
| Subdivision Type: | Country |
| Subdivision Name: | Cuba |
| Subdivision Type1: | Province |
| Subdivision Name1: | Granma |
| Area Total Km2: | 596 |
| Population As Of: | 2022 |
| Population Total: | 44,566 |
| Population Density Km2: | auto |
| Timezone: | EST |
| Utc Offset: | -5 |
| Coordinates: | 20.2608°N -76.5381°W |
| Elevation M: | 190 |
| Area Code: | +53-23 |
| Website: | https://www.guisa.gob.cu/es/ |
Guisa is a municipality and town in the Granma Province of Cuba. It is located 19km (12miles) south-east of Bayamo, the provincial capital.
In 2022, the municipality of Guisa had a population of 44,566.[1] With a total area of 596km2,[2] it has a population density of 75/km2.