| Guillermo Méndez | |
| Fullname: | Guillermo Andrés Méndez Aguilera |
| Birth Date: | 26 August 1994 |
| Birth Place: | Paysandú, Uruguay |
| Position: | Attacking midfielder |
| Youthclubs1: | Nacional |
| Years1: | 2012–2014 |
| Clubs1: | Standard Liège |
| Caps1: | 0 |
| Goals1: | 0 |
| Years2: | 2013 |
| Clubs2: | → Sint-Truiden (loan) |
| Caps2: | 19 |
| Goals2: | 3 |
| Years3: | 2014 |
| Clubs3: | → Alcorcón (loan) |
| Caps3: | 1 |
| Goals3: | 0 |
| Years4: | 2014–2017 |
| Clubs4: | Bella Vista |
| Years5: | 2017–2019 |
| Clubs5: | Unión Santa Fe |
| Caps5: | 11 |
| Goals5: | 0 |
| Years6: | 2018–2019 |
| Clubs6: | → Unión de Sunchales (loan) |
| Caps6: | 11 |
| Goals6: | 0 |
| Years7: | 2020 |
| Clubs7: | Huracán |
| Years8: | 2021–2022 |
| Clubs8: | La Luz |
| Years9: | 2022 |
| Years10: | 2023–2024 |
| Clubs10: | Rentistas |
| Caps10: | 8 |
| Goals10: | 1 |
| Nationalyears1: | 2011 |
| Nationalcaps1: | 16 |
| Nationalgoals1: | 2 |
| Pcupdate: | 19 January 2024 |
Guillermo Andrés Méndez Aguilera (born 26 August 1994) is a Uruguayan footballer.