| Guignicourt-sur-Vence | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason Guignicourt-sur-Vence.svg |
| Arrondissement: | Charleville-Mézières |
| Canton: | Nouvion-sur-Meuse |
| Insee: | 08203 |
| Postal Code: | 08430 |
| Mayor: | Brigitte Loizon[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Crêtes Préardennaises |
| Coordinates: | 49.6822°N 4.6528°W |
| Elevation M: | 167 |
| Area Km2: | 9.44 |
Guignicourt-sur-Vence (in French pronounced as /ɡiɲikuʁ syʁ vɑ̃s/) is a commune in the Ardennes department in northern France.