Guizhou or Gui Prefecture (Chinese: 媯州) was a zhou (prefecture) in imperial China, centering on modern Zhangjiakou, Hebei, China. It was created in 634 by the Tang dynasty and was later ceded by Later Jin to the Khitan-ruled Liao dynasty as one of the Sixteen Prefectures.
The administrative region of Guizhou in the Tang dynasty is in modern Zhangjiakou in northwestern Hebei. It probably includes parts of modern: